4-(Chloromethyl)-6-methyl-2-phenylpyrimidine CAS 131291-62-8
| CAS No. | 131291-62-8 |
| Molecular Formula | C12H11ClN2 |
| Molecular Weight | 218.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(Chloromethyl)-6-methyl-2-phenylpyrimidine (CAS 131291-62-8) is a high-purity analytical reference standard with the molecular formula C12H11ClN2 and a molecular weight of 218.68 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 4-(Chloromethyl)-6-methyl-2-phenylpyrimidine is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 218.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11ClN2 |
| Molecular Weight | 218.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 2-{2-chloropyrrolo[2,1-f][1,2,4]triazin-4-yl}acetamide (CAS 1312786-13-2)
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- n-(4-Chlorobenzyl)pyridin-3-amine (CAS 13159-78-9)
- 1-(Dimethylamino)-3-(2-(3-methoxyphenethyl)phenoxy)propan-2-ol hydrochloride (CAS 135261-74-4)
- Ethyl 2-amino-4-chloro-1H-indole-3-carboxylate (CAS 1126602-44-5)
- 2-phenylpiperazine dihydrochloride (CAS 872139-22-5)
- 6-Chloro-2-(4-methoxyphenyl)quinoline-4-carboxylic acid (CAS 116734-25-9)
- 3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-oxopropanoic acid (CAS 868707-77-1)
- 2-(Benzyloxy)-8-chloro-3-ethyl-1,7-naphthyridine (CAS 1802675-88-2)
- Finerenone Impurity 281 (CAS CATO-C4X-2880281)
- Fmoc-Thr(tBu)-Thr(Psi(Me,Me)pro)-OH (CAS 1676104-73-6)
- 7-Chloro-2-methyl-1H-pyrrolo[2,3-c]pyridine (CAS 874013-97-5)
- D-[Asp]9-Semaglutide (CAS CATO-CPTD788631)
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