1-(2,3-Dichlorophenyl)-3-phenylurea CAS 13142-52-4

Purity 97%+In StockPharmaceutical Standards
CAS No.13142-52-4
Molecular FormulaC13H10Cl2N2O
Molecular Weight281.14 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(2,3-Dichlorophenyl)-3-phenylurea CAS 13142-52-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 281.14 g/mol gives 1-(2,3-Dichlorophenyl)-3-phenylurea distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1-(2,3-Dichlorophenyl)-3-phenylurea (CAS 13142-52-4), molecular formula C13H10Cl2N2O and molecular weight 281.14 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1-(2,3-Dichlorophenyl)-3-phenylurea (C13H10Cl2N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC13H10Cl2N2O
Molecular Weight281.14 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1960
Halogen ContentCl-containing
Nitrogen Atoms2

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