(2S)-2-Amino-3-[6-(Difluoromethyl)-1H-Indol-3-Yl]Propanoic Acid CAS 131490-35-2
| CAS No. | 131490-35-2 |
| Molecular Formula | C12H12F2N2O2 |
| Molecular Weight | 254.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(2S)-2-Amino-3-[6-(Difluoromethyl)-1H-Indol-3-Yl]Propanoic Acid (CAS 131490-35-2), molecular formula C12H12F2N2O2 and molecular weight 254.23 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C12H12F2N2O2, (2S)-2-Amino-3-[6-(Difluoromethyl)-1H-Indol-3-Yl]Propanoic Acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 254.23 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (2S)-2-Amino-3-[6-(Difluoromethyl)-1H-Indol-3-Yl]Propanoic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H12F2N2O2 |
| Molecular Weight | 254.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related S Standards
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Recommended Standards
- 2,2,2-Trifluoroethyl (4,5-dimethylthiazol-2-yl)carbamate (CAS 1306606-07-4)
- 2,2,2-Trifluoro-1-(4-(methylsulfonyl)phenyl)ethan-1-ol (CAS 1350349-33-5)
- Ethyl 2-(methylamino)-4-(trifluoromethyl)thiazole-5-carboxylate (CAS 1280787-22-5)
- 2,6-Difluoro-N-(1-methyl-5-oxopyrrolidin-3-yl)benzamide (CAS 1396843-85-8)
- 1-Ethyl-3-oxo-1,2,3,4-tetrahydroquinoxaline-6-carboxylic acid (CAS 1031655-17-0)
- 4-Ethoxypyrimidin-5-amine (CAS 55150-17-9)
- Pyrido[3,2-d]pyrimidin-2(1H)-one (CAS 116598-88-0)
- 4-Pentylcyclohexanecarboxylic Acid (cis- and trans- mixture) (CAS 38792-89-1)
- (1-(4-Bromophenyl)-3-methylcyclobutyl)methanamine (CAS 1341584-29-9)
- 1-((1H-pyrazol-1-yl)methyl)-1H-pyrazole-4-carboxylic acid (CAS 1263211-59-1)
- (3-Methyl-4-(methylthio)phenyl)boronic acid (CAS 221031-07-8)
- Ethyl 2-(2-fluoro-3-(trifluoromethyl)phenyl)-acetate (CAS 1260854-01-0)
- （Z)-Pyriminobac-methyl (CAS 147411-70-9)
- Insulin Degludec Impurity 19 (CAS CATO-C4X-215719)
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