5-Chloro-4-hydroxy-8-methoxyquinoline-3-carbohydrazide CAS 1315344-84-3
| CAS No. | 1315344-84-3 |
| Molecular Formula | C11H10ClN3O3 |
| Molecular Weight | 267.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Chloro-4-hydroxy-8-methoxyquinoline-3-carbohydrazide.
5-Chloro-4-hydroxy-8-methoxyquinoline-3-carbohydrazide (CAS 1315344-84-3), molecular formula C11H10ClN3O3 and molecular weight 267.67 g/mol, is a CATO reference standard with documented purity and traceability.
5-Chloro-4-hydroxy-8-methoxyquinoline-3-carbohydrazide (C11H10ClN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Chloro-4-hydroxy-8-methoxyquinoline-3-carbohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10ClN3O3 |
| Molecular Weight | 267.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 5-(2-Chloro-5-nitrophenyl)-3-propyl-1,2,4-oxadiazole (CAS 1119505-95-1)
- 6-(4-Chloro-3-nitrophenyl)-5-methyl-4,5-dihydropyridazin-3(2h)-one (CAS 117397-88-3)
- Ethyl 5-chloro-7-methyl-2-oxo-2H-pyrano[3,2-c]pyridine-3-carboxylate (CAS 1254830-70-0)
- 2-(7-Chloro-6-methoxy-4-oxoquinolin-1(4H)-yl)acetic acid (CAS 1315349-38-2)
- 7-Chloro-4-hydroxy-6-methoxyquinoline-3-carbohydrazide (CAS 1315352-65-8)
- 7-Chloro-6-methoxy-1-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 1315373-27-3)
- 3-(2-chloro-6-methoxyphenyl)-5-methyl-1,2-oxazole-4-carboxylic acid (CAS 1364523-60-3)
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Recommended Standards
- 7-Amino-2-chloro-8-ethyl-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide (CAS 1314997-72-2)
- 3-(2-Carboxyethyl)-4-chloro-1H-indole-2-carboxylic acid (CAS 130798-49-1)
- Ethyl 1-(6-chloropyridin-2-yl)-5-hydroxy-1H-pyrazole-4-carboxylate (CAS 1279204-71-5)
- 1-(2-(3-Chlorophenyl)-2-hydroxyethyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1338691-83-0)
- (4-Fluorophenyl)methanesulfonamide (CAS 500108-01-0)
- (1-(tert-Butoxycarbonyl)-4-chloro-7-methoxy-1H-indol-2-yl)boronic acid (CAS 1203844-60-3)
- 4,6-Dichloroisoxazolo[5,4-d]pyrimidine (CAS 1197193-09-1)
- N-(3,4-Difluorophenyl)-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}acetamide (CAS 303091-73-8)
- 3-Methoxy-2-methyl-1-propanamine (CAS 26331-99-7)
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- Methyl 4-amino-3-(propylamino)benzoate (CAS 675138-83-7)
- Methyl 6-hydroxy-2,2,6-trimethylhept-4-ynoate (CAS 2718220-25-6)
- (1-ethylazetidin-3-yl)methanol (CAS 1480536-66-0)
- D-Thr5-Tirzepatide (CAS CATO-CPTD788926)
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