4-((7-Fluoroquinolin-4-yl)amino)benzoic acid CAS 1315372-63-4
| CAS No. | 1315372-63-4 |
| Molecular Formula | C16H11FN2O2 |
| Molecular Weight | 282.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-((7-Fluoroquinolin-4-yl)amino)benzoic acid (C16H11FN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
4-((7-Fluoroquinolin-4-yl)amino)benzoic acid (CAS 1315372-63-4), molecular formula C16H11FN2O2 and molecular weight 282.27 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-((7-Fluoroquinolin-4-yl)amino)benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H11FN2O2 |
| Molecular Weight | 282.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoroquinolin Standards
- 1-(4-((6-Fluoroquinolin-4-yl)amino)phenyl)ethan-1-one (CAS 1018162-02-1)
- 2-(4-(6-Fluoroquinolin-4-yl)cyclohexyl)acetic acid (CAS 1923836-20-7)
- 5-(((5-Fluoroquinolin-8-yl)methyl)thio)-4-methyl-4h-1,2,4-triazol-3-amine (CAS 1241183-24-3)
- (1-((6-Fluoroquinolin-2-yl)methyl)piperidin-2-yl)methanol (CAS 1221411-09-1)
- (1-((6-Fluoroquinolin-2-yl)methyl)piperidin-4-yl)methanol (CAS 1221411-10-4)
- 1-(8-Fluoroquinolin-3-yl)-4-methyl-2,6,7-trioxa-1-borabicyclo[2.2.2]octan-1-uide (CAS 1280293-58-4)
- N-((6-Fluoroquinolin-2-yl)methyl)-2-(pyrrolidin-1-yl)ethanamine (CAS 1221411-12-6)
- 5-(((6-Fluoroquinolin-8-yl)methyl)thio)-1,3,4-thiadiazol-2-amine (CAS 1094545-76-2)
Recommended Standards
- 4-Fluorobenzenecarbaldehyde N-(3-oxo-3,4-dihydro-2-quinoxalinyl)hydrazone (CAS 129227-27-6)
- 7-Fluoro-3-(2-oxo-2-phenyl-ethylidene)-3,4-dihydro-1H-quinoxalin-2-one (CAS 1380572-42-8)
- 1-(4-Fluoro-5-methyl-2-nitrophenyl)piperidine-4-carboxylic acid (CAS 1261079-65-5)
- 3-[5-(methanesulfonylmethyl)-1,3,4-oxadiazol-2-yl]benzoic acid (CAS 1409023-06-8)
- 2-(4-Chloro-5-fluoropyridin-2-yl)ethan-1-amine (CAS 1393573-01-7)
- 5-Fluoroimidazo[1,2-a]pyridine hydrochloride (CAS 198896-14-9)
- 4-(6-Hydroxy-2-propylpyrimidin-4-yl)-1-methylpyrrolidin-2-one (CAS 1708208-51-8)
- Tert-butyl ((4-(2-(trifluoromethyl)benzyl)piperidin-4-yl)methyl)carbamate (CAS 2197054-42-3)
- 2-(5-Phenyl-1H-tetrazol-1-yl)-3-(thiophen-2-yl)acrylic acid (CAS 36283-09-7)
- 2-(((Benzyloxy)carbonyl)amino)-2-cyclohexylacetic acid (CAS 93025-71-9)
- 1-(Pyrrolidin-3-yl)-1H-1,2,4-triazol-3-amine (CAS 746580-84-7)
- Ethyl (3R,4R)-4-hydroxypyrrolidine-3-carboxylate hydrochloride (CAS 80616-45-1)
- 6-(Aminomethyl)-1,2,4-triazin-5(4H)-one (CAS 867163-25-5)
- Hexapeptide-9 (CAS 1228371-11-6)
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