3-[2-(1-Methanesulfonyl-piperidin-4-yl)-6-methyl-pyrimidin-4-yl]-propionic acid CAS 1316221-27-8
| CAS No. | 1316221-27-8 |
| Molecular Formula | C14H21N3O4S |
| Molecular Weight | 327.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-[2-(1-Methanesulfonyl-piperidin-4-yl)-6-methyl-pyrimidin-4-yl]-propionic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-[2-(1-Methanesulfonyl-piperidin-4-yl)-6-methyl-pyrimidin-4-yl]-propionic acid (CAS 1316221-27-8), a certified reference material (molecular formula C14H21N3O4S, MW 327.40 g/mol) for analytical method development and quality control.
The molecular framework of 3-[2-(1-Methanesulfonyl-piperidin-4-yl)-6-methyl-pyrimidin-4-yl]-propionic acid (C14H21N3O4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-[2-(1-Methanesulfonyl-piperidin-4-yl)-6-methyl-pyrimidin-4-yl]-propionic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H21N3O4S |
| Molecular Weight | 327.40 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methanesulfonyl Standards
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- 1-Methanesulfonyl-4-[4-(trifluoromethoxy)phenoxy]benzene (CAS 286844-91-5)
- 4-(3-Methanesulfonyl-4-methyl-6-phenylpyridin-2-yl)morpholine (CAS 339017-11-7)
- 5-Methanesulfonyl-4-(4-methylpiperazin-1-yl)-2-phenylpyrimidine (CAS 478067-75-3)
- 1-benzyl-6-methanesulfonyl-3-methoxy-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 1372100-28-1)
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Recommended Standards
- 3-(6-Methyl-2-(1-(methylsulfonyl)piperidin-3-yl)pyrimidin-4-yl)propanoic acid (CAS 1316218-52-6)
- 3-(2-Methyl-6-(1-(methylsulfonyl)piperidin-3-yl)pyrimidin-4-yl)propanoic acid (CAS 1316222-87-3)
- 5-Benzo[b]thiophen-3-ylmethylene-3-methyl-2-morpholin-4-yl-3,5-dihydro-imidazol-4-one (CAS 1312024-79-5)
- 3-(2-Methyl-6-(1-(methylsulfonyl)piperidin-4-yl)pyrimidin-4-yl)propanoic acid (CAS 1316226-03-5)
- 5-Methyl-2-phenyl-1H-imidazole-4-carboxylic acid hydrate (CAS 1559064-09-3)
- 3'-Chloro-4'-methyl-[1,1'-biphenyl]-4-carboxylic acid (CAS 885962-94-7)
- Tert-butyl n-[4-amino-3-(trifluoromethyl)phenyl]carbamate (CAS 1016506-18-5)
- N-Butyl-3,4-dihydroxybenzamide (CAS 98116-92-8)
- Piperazine Dihydriodide (CAS 58464-47-4)
- n-Heptylbenzene-2,3,4,5,6-d5 (CAS 1219799-19-5)
- Ethyl 4-cyano-2-(trifluoromethyl)benzoate (CAS 1807078-13-2)
- 2-Methoxy-5-nitrothiophene (CAS 30549-16-7)
- 4-aminopyridine-3-boronic acid (CAS 959957-75-6)
- Semaglutide Impurity 166 (CAS 1395881-03-4)
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