3-(1-Acetyl-piperazin-2-yl)-benzamide CAS 1316221-75-6
| CAS No. | 1316221-75-6 |
| Molecular Formula | C13H17N3O2 |
| Molecular Weight | 247.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-(1-Acetyl-piperazin-2-yl)-benzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-(1-Acetyl-piperazin-2-yl)-benzamide (CAS 1316221-75-6), molecular formula C13H17N3O2 and molecular weight 247.29 g/mol, is a CATO reference standard with documented purity and traceability.
3-(1-Acetyl-piperazin-2-yl)-benzamide (C13H17N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C13H17N3O2 |
| Molecular Weight | 247.29 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 3 |
Related Acetyl Standards
- 3-(Piperazin-2-yl)-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid (CAS 1273566-41-8)
- 4-Piperazin-1-yl-6-piperidin-1-ylpyrimidine (CAS 1204296-32-1)
- 2-Methyl-4-(piperazin-1-ylsulfonyl)thiazole (CAS 1258826-79-7)
- 2-Methyl-4-(piperazin-1-yl)-6-(pyrrolidin-1-yl)pyrimidine (CAS 1706447-61-1)
- 4-(4-Piperazin-2-yl-phenyl)morpholine (CAS 864685-27-8)
- 4-Ethyl-2-piperazin-1-yl-1,3-benzothiazole (CAS 1018498-64-0)
- 6-Ethyl-2-piperazin-1-yl-1,3-benzothiazole (CAS 1018566-85-2)
- 1-(Piperazin-1-ylsulfonyl)azepane (CAS 884380-90-9)
Recommended Standards
- Benzyl 2-methyl-5-oxopiperidine-1-carboxylate (CAS 1314395-91-9)
- (2S,3S)-3-{[(tert-Butoxy)carbonyl]amino}-2-hydroxy-4-methylpentanoic acid (CAS 1318775-44-8)
- 1-Butyl-4-methoxy-1H-indole-3-carboxylic acid (CAS 1313042-98-6)
- (2R,3S)-3-{[(tert-Butoxy)carbonyl]amino}-2-hydroxy-4-methylpentanoic acid (CAS 1318775-45-9)
- (4-Bromopyridin-2-yl)-pyrazin-2-yl-amine (CAS 1636895-40-3)
- methyl furo[3,2-c]pyridine-6-carboxylate (CAS 478149-29-0)
- 1-((Tetrahydro-2H-pyran-4-yl)methyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1341045-34-8)
- trans-1-Benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylic acid hydrochloride (CAS 1013117-42-4)
- 2-Oxa-7-azaspiro[3.5]nonane 2,2,2-trifluoroacetate (CAS 1257381-44-4)
- 2-((4-Chlorobenzyl)oxy)ethane-1-sulfonyl chloride (CAS 1484903-48-1)
- (2R,5R)-Methyl 5-methoxytetrahydrofuran-2-carboxylate (CAS 174689-91-9)
- 3-Nitro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile (CAS 775351-58-1)
- 5-(1-Methyl-piperidin-4-yloxy)-pyridin-2-ylamine (CAS 1249322-37-9)
- D-Ala28-Tirzepatide (CAS CATO-CPTD788906)
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