(S,6Z,8E,10E)-5-hydroxy-12-oxoicosa-6,8,10-trienoic acid CAS 131721-27-2

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

(S,6Z,8E,10E)-5-hydroxy-12-oxoicosa-6,8,10-trienoic acid (CAS 131721-27-2) is a high-purity analytical reference standard with the molecular formula C20H32O4 and a molecular weight of 336.47 g/mol.

The molecular framework of (S,6Z,8E,10E)-5-hydroxy-12-oxoicosa-6,8,10-trienoic acid (C20H32O4) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

As a certified reference material (CRM), (S,6Z,8E,10E)-5-hydroxy-12-oxoicosa-6,8,10-trienoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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