131740-09-5 D48MS3A6N9 Alvocidib [USAN:INN:BAN] Alvocidib hydrochloride [USAN] 4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-((3S,4R)-3-hydroxy-1-methyl-4-piperidinyl)-, hydrochloride 4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-4-piperidinyl)-, hydrochloride, cis-(-)- Alvocidib hydrochloride HMR 1275 MDL 107826A Flavopiridol NSC 649890 UNII-D48MS3A6N9 Alvocidib HL 275 L 86 8275 MDL 107,826A HL-275 HMR-1275 L86-8275 MDL-107826A CAS 131740-09-5

Description

The occurrence of 131740-09-5 D48MS3A6N9 Alvocidib [USAN:INN:BAN] Alvocidib hydrochloride [USAN] 4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-((3S,4R)-3-hydroxy-1-methyl-4-piperidinyl)-, hydrochloride 4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-4-piperidinyl)-, hydrochloride, cis-(-)- Alvocidib hydrochloride HMR 1275 MDL 107826A Flavopiridol NSC 649890 UNII-D48MS3A6N9 Alvocidib HL 275 L 86 8275 MDL 107,826A HL-275 HMR-1275 L86-8275 MDL-107826A is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

131740-09-5 D48MS3A6N9 Alvocidib [USAN:INN:BAN] Alvocidib hydrochloride [USAN] 4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-((3S,4R)-3-hydroxy-1-methyl-4-piperidinyl)-, hydrochloride 4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-4-piperidinyl)-, hydrochloride, cis-(-)- Alvocidib hydrochloride HMR 1275 MDL 107826A Flavopiridol NSC 649890 UNII-D48MS3A6N9 Alvocidib HL 275 L 86 8275 MDL 107,826A HL-275 HMR-1275 L86-8275 MDL-107826A (CAS 131740-09-5) is a high-purity analytical reference standard with the molecular formula C21H20ClNO5HCl and a molecular weight of 438.30 g/mol.

Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 131740-09-5 D48MS3A6N9 Alvocidib [USAN:INN:BAN] Alvocidib hydrochloride [USAN] 4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-((3S,4R)-3-hydroxy-1-methyl-4-piperidinyl)-, hydrochloride 4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-4-piperidinyl)-, hydrochloride, cis-(-)- Alvocidib hydrochloride HMR 1275 MDL 107826A Flavopiridol NSC 649890 UNII-D48MS3A6N9 Alvocidib HL 275 L 86 8275 MDL 107,826A HL-275 HMR-1275 L86-8275 MDL-107826A is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 438.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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