(2-(Trifluoromethyl)thiazol-5-yl)methanol CAS 131748-97-5
| CAS No. | 131748-97-5 |
| Molecular Formula | C5H4F3NOS |
| Molecular Weight | 183.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2-(Trifluoromethyl)thiazol-5-yl)methanol.
(2-(Trifluoromethyl)thiazol-5-yl)methanol (CAS 131748-97-5), molecular formula C5H4F3NOS and molecular weight 183.15 g/mol, is a CATO reference standard with documented purity and traceability.
(2-(Trifluoromethyl)thiazol-5-yl)methanol (C5H4F3NOS) contains an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2-(Trifluoromethyl)thiazol-5-yl)methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H4F3NOS |
| Molecular Weight | 183.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Trifluoromethyl Standards
- alpha-(Trifluoromethyl)thiazole-2-methanol (CAS 1206673-52-0)
- alpha-(Trifluoromethyl)thiazole-5-methanol (CAS 1206673-54-2)
- [5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]methanamine (CAS 1260663-10-2)
- [2-(trifluoromethyl)-1,3-thiazol-4-yl]methanol (CAS 133046-47-6)
- [5-(Trifluoromethyl)-1,3-thiazol-2-yl]methanol (CAS 1434142-11-6)
- (5-(Trifluoromethyl)thiazol-4-yl)methanol (CAS 1478719-81-1)
- (4-(Trifluoromethyl)thiazol-5-yl)methanol (CAS 1708179-28-5)
- (3-(Trifluoromethyl)isothiazol-5-yl)methanol (CAS 1934453-22-1)
Recommended Standards
- 4-(Difluoromethoxy)-1H-indole (CAS 1315364-47-6)
- 6,7-Difluoro-3,4-dihydroquinolin-2(1H)-one (CAS 132669-27-3)
- 7-(Difluoromethoxy)-1H-indole (CAS 1315362-68-5)
- 5-(Difluoromethyl)-2-methoxybenzonitrile (CAS 1261861-81-7)
- 2-Hydroxy-4-(hydroxymethyl)benzaldehyde (CAS 156605-23-1)
- 2-Fluorobenzoyl cyanide (CAS 80277-41-4)
- N-(1-(3,4-dichlorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl)-2-nitrobenzamide (CAS 400086-18-2)
- 3,3'-(Piperazine-1,4-diyl)bis(propan-1-ol) (CAS 28765-60-8)
- 2-Bromo-5-(pyridin-3-ylmethoxy)pyrazine (CAS 1877094-05-7)
- 3-(5-Chlorofuran-2-yl)prop-2-en-1-amine (CAS 1344788-17-5)
- Ethyl 1-aminocyclopentane-1-carboxylate (CAS 1664-35-3)
- 6-chloro-5-[3-(1-oxo-1,4-thiazinan-4-yl)prop-1-ynyl]-1H-pyrimidin-4-one (CAS 2528573-58-0)
- 2-Bromo-N1-(tert-butyl)benzene-1,4-diamine (CAS 1249234-21-6)
- Semaglutide impurity 89 (CAS CATO-C4X-222689)
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