Fmoc-D-Cys(tBu)-OH CAS 131766-22-8
| CAS No. | 131766-22-8 |
| Molecular Formula | C22H25NO4S |
| Molecular Weight | 399.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 399.50 g/mol gives Fmoc-D-Cys(tBu)-OH distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Fmoc-D-Cys(tBu)-OH (CAS 131766-22-8), molecular formula C22H25NO4S and molecular weight 399.50 g/mol, is a CATO reference standard with documented purity and traceability.
Fmoc-D-Cys(tBu)-OH (C22H25NO4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H25NO4S |
| Molecular Weight | 399.50 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Fmoc Standards
- FMOC-O-tert-butyl-L-serine-<SUP>13</SUP>C<SUB>3</SUB>,<SUP>15</SUP>N (CAS 1217448-78-6)
- Fmoc-Cys(tBu)-OH (CAS 67436-13-9)
- Fmoc-2-aminoindane-2-carboxylic Acid (CAS 135944-07-9)
- (R)-Fmoc-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid (CAS 204317-98-6)
- Fmoc-NH-PEG2-CH2CH2COOH (CAS 872679-70-4)
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- N-Fmoc-DL-1-aminoindane-1-carboxylic Acid (CAS 214139-28-3)
- Fmoc-D-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (CAS 130309-33-0)
Recommended Standards
- N-((4-Methylphenyl)sulfonyl)(4-(3-phenylprop-2-enyl)piperazinyl)formamide (CAS 1025561-75-4)
- Boc-Cys(Fm)-OH (CAS 84888-35-7)
- (2R,3S,4R,5R)-2,3,4,5,6-Pentahydroxy-N-(3-(triethoxysilyl)propyl)hexanamide (CAS 104275-58-3)
- Blonanserin Impurity 4 (CAS 2243797-97-7)
- 5,6-Dichloro-3-iodo-1H-indazole (CAS 1426421-76-2)
- 2-(1-(2-Methoxybenzyl)-3-oxopiperazin-2-yl)acetic acid (CAS 1033600-22-4)
- 2’-Amino-4’-bromoacetophenone (CAS 123858-51-5)
- 3-Nitro-5-(trifluoromethyl)pyridine (CAS 1214323-87-1)
- 1-tert-Butyl 2-methyl 4,4-difluoro-5-methylpyrrolidine-1,2-dicarboxylate (CAS 1956306-63-0)
- 4-(Furan-2-yl)nicotinic acid (CAS 1261961-41-4)
- 4-((5-Bromopyrimidin-2-yl)thio)aniline (CAS 849235-61-6)
- 4-(Naphthalen-1-yloxy)butanoic acid (CAS 16563-45-4)
- (9h-Fluoren-9-yl)methyl 2-(3-hydroxypropyl)pyrrolidine-1-carboxylate (CAS 1344238-75-0)
- Glucagon receptor antagonist I (CAS 438618-32-7)
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