Lansoprazole Impurity 12 CAS 131926-97-1

Description

Compared with other compounds in its class, the molecular weight of 271.34 g/mol gives Lansoprazole Impurity 12 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Lansoprazole Impurity 12 (CAS 131926-97-1) is a certified pharmaceutical impurity reference standard with the molecular formula C14H13N3OS and a molecular weight of 271.34 g/mol.

The molecular framework of Lansoprazole Impurity 12 (C14H13N3OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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