7-[5-O-[(1,1-Dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-β -D-ribofuranosyl]-4-methoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amine CAS 131981-22-1
| CAS No. | 131981-22-1 |
| Molecular Formula | C21H34N4O5Si |
| Molecular Weight | 450.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 450.60 g/mol gives 7-[5-O-[(1,1-Dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-β -D-ribofuranosyl]-4-methoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
7-[5-O-[(1,1-Dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-β -D-ribofuranosyl]-4-methoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amine (CAS 131981-22-1), molecular formula C21H34N4O5Si and molecular weight 450.60 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, 7-[5-O-[(1,1-Dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-β -D-ribofuranosyl]-4-methoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 450.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 7-[5-O-[(1,1-Dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-β -D-ribofuranosyl]-4-methoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H34N4O5Si |
| Molecular Weight | 450.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 4 |
Related O Standards
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- 2′-[Bis(1,1-dimethylethyl)phosphino]-5,5′,6,6′,7,7′,8,8′-octahydro-N,N-dimethyl[1,1′-binaphthalen]-2-amine (CAS 378787-32-7)
- 1,1-Dimethylethyl 4-(10-oxo-12-phenyl-3,6,11-trioxa-9-azadodec-1-yl)-1-piperazinecarboxylate (CAS 2382771-34-6)
- 1,1'-[(1Z)-1-(1,1-Dimethylethyl)-1,2-ethenediyl]bis[1,1-diphenylphosphine] (CAS 66493-16-1)
- (E)-3-[5-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]-4-(4-fluorophenyl)-2,6-bis(1-methylethyl)-3-pyridinyl]-2-propenal (E)-3-[5-tert-Butyldimethylsilyloxymethyl-2,6-diisopropyl-4-(4-fluorophenyl)-pyrid-3-yl]-prop-2-enal 124863-84-9 (CAS 124863-84-9)
- 6-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]-2,2,3,3,9,9,10,10-octamethyl-4,8-dioxa-3,9-disilaundecan-6-amine (CAS 102522-47-4)
- BIS(1,1-DIMETHYLETHYL)-(2-IODO-4-NITROPHENYL) IMIDODICARBONATE (CAS 395639-04-0)
- 5-(1,1-Dimethylethyl)-2-hydroxy-3-(triphenylsilyl)benzaldehyde (CAS 1254097-55-6)
Recommended Standards
- Glipizide EP Impurity I (CAS 10079-35-3)
- OS-3-106, >98% (HPLC) (CAS 1580000-17-4)
- Rivenprost (CAS 256382-08-8)
- Carbamic acid, N-[(1S)-2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-1-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]ethyl]-, 1,1-dimethylethyl ester (CAS 1956436-22-8)
- N-((1H-Benzo[d][1,2,3]triazol-1-yl)methyl)-2,3,4,5,6-pentafluoroaniline (CAS 303090-97-3)
- Ivacaftor (CAS 873054-44-5)
- 5-Fluoro-ADB-PINACA (CAS 1801338-21-5)
- (2-Methoxy-4,6-dimethylphenyl)methanol (CAS 733768-81-5)
- 4-Methyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-imidazole (CAS 1392418-38-0)
- Mono(1,1'-bis(4-methoxyphenyl)-[4,4'-bipyridine]-1,1'-diium) monochloride (CAS 100906-93-2)
- 7-(Trifluoromethoxy)benzo[d]oxazol-2-amine (CAS 1806501-06-3)
- 5-Ethynyl-6-methylnicotinic acid (CAS 1824300-16-4)
- (S)-3-Iodo-1-methyl-pyrrolidine (CAS 1354010-60-8)
- Peptide Impurity 26 (CAS 1350456-66-4)
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