Duloxetine Impurity 14 CAS 132335-44-5

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.132335-44-5
Molecular FormulaC9H15NOS
Molecular Weight185.29 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Duloxetine Impurity 14 CAS 132335-44-5 chemical structure

Description

CATO supplies Duloxetine Impurity 14 (CAS 132335-44-5), a pharmacopoeial impurity reference standard (molecular formula C9H15NOS, MW 185.29 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Duloxetine Impurity 14 (C9H15NOS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC9H15NOS
Molecular Weight185.29 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1994
Nitrogen Atoms1
Sulfur Atoms1

Related Duloxetine Standards

Recommended Standards

Why CATO?