2-Fluoro-5-methyl-4-(trifluoromethyl)-benzoyl chloride CAS 1323966-18-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1323966-18-2
Molecular FormulaC9H5ClF4O
Molecular Weight240.58 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Fluoro-5-methyl-4-(trifluoromethyl)-benzoyl chloride CAS 1323966-18-2 chemical structure

Description

The molecular framework of 2-Fluoro-5-methyl-4-(trifluoromethyl)-benzoyl chloride (C9H5ClF4O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

2-Fluoro-5-methyl-4-(trifluoromethyl)-benzoyl chloride (CAS 1323966-18-2), molecular formula C9H5ClF4O and molecular weight 240.58 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC9H5ClF4O
Molecular Weight240.58 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF/Cl-containing

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