1-(4-Chloro-2-fluoro-3-methoxyphenyl)ethan-1-one CAS 1323966-44-4
| CAS No. | 1323966-44-4 |
| Molecular Formula | C9H8ClFO2 |
| Molecular Weight | 202.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(4-Chloro-2-fluoro-3-methoxyphenyl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-(4-Chloro-2-fluoro-3-methoxyphenyl)ethan-1-one (CAS 1323966-44-4), molecular formula C9H8ClFO2 and molecular weight 202.61 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 1-(4-Chloro-2-fluoro-3-methoxyphenyl)ethan-1-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 202.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H8ClFO2 |
| Molecular Weight | 202.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-(2-Chloro-4-fluoro-5-methylphenyl)acetic acid (CAS 1000522-29-1)
- 2-Chloro-1-(2-fluoro-4-methoxyphenyl)ethan-1-one (CAS 1028298-97-6)
- Methyl 2-(2-chloro-6-fluorophenyl)acetate (CAS 103473-99-0)
- Methyl 2-(4-chloro-3-fluorophenyl)acetate (CAS 1035262-89-5)
- Methyl 2-chloro-2-(4-fluorophenyl)acetate (CAS 1036273-29-6)
- 3-Chloro-1-(5-fluoro-2-hydroxyphenyl)propan-1-one (CAS 104147-77-5)
- 2-(2-Chloro-6-fluorophenyl)propanoic acid (CAS 1083172-73-9)
- 6- Chloro- 2- (ethylamino) pyridine- 3- carbonyl Fluoride (CAS 1092523-22-2)
Recommended Standards
- 4-Chloro-3-ethoxy-2-fluorobenzaldehyde (CAS 1323966-27-3)
- Methyl 5-(chloromethyl)-2-fluorobenzoate (CAS 1338563-94-2)
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- N-Dechloroethyl Cyclophosphamide-d4 (CAS 1346600-68-7)
- 3-Oxo-2-(tetrahydro-2H-pyran-4-yl)-2,3-dihydropyridazine-4-carboxylic acid (CAS 1443289-09-5)
- 3-Hydroxy-N-(3-methoxyphenyl)-2-naphthamide (CAS 62553-86-0)
- 2-(3-Ethoxyphenyl)-6-methylquinoline-4-carboxylic acid (CAS 438212-75-0)
- 7-Chloro-2-(3,4-dimethoxyphenyl)-8-methylquinoline-4-carboxylic acid (CAS 588696-86-0)
- 3,4-Dichloro-2-nitrobenzenesulfonamide (CAS 1806367-57-6)
- 3-(2-(2,5-Dioxopyrrolidin-3-yl)acetyl)-4-oxocyclohexyl acetate (CAS 6953-00-0)
- 4-Aminothiophene-3-carboxylic acid hydrochloride (CAS 1049777-16-3)
- 2-Bromo-butan-2-ylboronic acid pinacol ester (CAS 2379550-54-4)
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- Semaglutide impurity 69 (CAS CATO-C4X-222669)
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