4-{[1,1'-Biphenyl]-4-carbonyl}-8-methyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid CAS 1326808-63-2
| CAS No. | 1326808-63-2 |
| Molecular Formula | C22H24N2O4 |
| Molecular Weight | 380.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-{[1,1'-Biphenyl]-4-carbonyl}-8-methyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (C22H24N2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-{[1,1'-Biphenyl]-4-carbonyl}-8-methyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326808-63-2) is a high-purity analytical reference standard with the molecular formula C22H24N2O4 and a molecular weight of 380.44 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-{[1,1'-Biphenyl]-4-carbonyl}-8-methyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H24N2O4 |
| Molecular Weight | 380.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
Related Biphenyl Standards
- 1-([1,1'-Biphenyl]-4-yl)-3-((4-chloro-3-nitrophenyl)amino)propan-1-one (CAS 882748-41-6)
- [1,1'-Biphenyl]-4-yl 2,4,6-trichloropyrimidine-5-carboxylate (CAS 87848-06-4)
- 4-{[1,1'-Biphenyl]-4-carbonyl}-8-methyl-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid (CAS 1326809-54-4)
- N-([1,1'-biphenyl]-2-yl)-2-([1,1'-biphenyl]-4-yloxy)acetamide (CAS 332018-21-0)
- (S)-2-([1,1'-Biphenyl]-4-ylmethyl)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid hydrochloride (CAS 1217857-74-3)
- 5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid (CAS 1361408-20-9)
- (R)-2-([1,1'-biphenyl]-4-ylmethyl)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid (CAS 959576-43-3)
- 7-{[1,1'-biphenyl]-4-yl}-3-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidine (CAS 685109-53-9)
Recommended Standards
- Benzyl 4-(2-oxo-3-phenyl-1,3-oxazolidin-5-yl)piperidine-1-carboxylate (CAS 1315619-14-7)
- 3-(4-(((9h-Fluoren-9-yl)methoxy)carbonyl)piperazin-1-yl)propanoic acid (CAS 1339485-97-0)
- (2E)-3-[1-(Triphenylmethyl)-1H-imidazol-4-yl]prop-2-enoic acid (CAS 125872-93-7)
- 2-(4-(((9H-fluoren-9-yl)methoxy)carbonyl)piperazin-1-yl)propanoic acid (CAS 1341588-25-7)
- rel-(1S,2S,4S)-Bicyclo[2.2.1]hept-5-ene-2-carboxylate (potassium) (CAS 2230623-55-7)
- 2-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)acetic acid (CAS 281676-77-5)
- Indium(III) chloride hydrate (CAS 1332498-33-5)
- 6-Bromo-2-(tert-butyl)quinoline-4-carbonitrile (CAS 1416440-43-1)
- (1,1-Dimethylethyl)dimethyl[(1-methyl-3-butynyl)oxy]silane (CAS 80186-44-3)
- (5-Bromo-3-(trifluoromethyl)pyridin-2-yl)methanol (CAS 1206968-90-2)
- tert-Butyl 2-benzylisoindoline-1-carboxylate (CAS 84385-22-8)
- 1,4,7,8-Tetrabromodibenzo[b,d]furan (CAS 617708-57-3)
- 2-Methyl-N-(m-tolyl)aniline (CAS 34801-11-1)
- Semaglutide impurity 268 (CAS CATO-C4X-2226268)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com