4-(4-Chloro-2-fluorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid CAS 1326808-79-0
| CAS No. | 1326808-79-0 |
| Molecular Formula | C18H22ClFN2O4 |
| Molecular Weight | 384.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 384.83 g/mol gives 4-(4-Chloro-2-fluorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-(4-Chloro-2-fluorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326808-79-0), a certified reference material (molecular formula C18H22ClFN2O4, MW 384.83 g/mol) for analytical method development and quality control.
Structurally, 4-(4-Chloro-2-fluorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (C18H22ClFN2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 384.83 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H22ClFN2O4 |
| Molecular Weight | 384.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- (3-(2-Chloro-6-fluorophenyl)-5-methylisoxazol-4-yl)(6-methyl-3,4-dihydroquinolin-1(2H)-yl)methanone (CAS 1024580-16-2)
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Recommended Standards
- 1242958-23-1 1-{[1-(2-Chloropyridin-3-yl)-1H-pyrrol-2-yl]carbonyl}-4-(4-fluorophenyl)piperazine MFCD15732298 (CAS 1242958-23-1)
- Cefdinir Impurity 92 (CAS 110198-95-3)
- N'-[2-(4-Chlorophenoxy)ethanimidoyl]-5-methyl-3-phenyl-1,2-oxazole-4-carbohydrazide (CAS 338405-55-3)
- (E)-1-[2-(4-Chlorophenyl)-4-methyl-1,3-thiazol-5-yl]-3-(2-nitrophenyl)-2-propen-1-one (CAS 1211932-77-2)
- Ethyl 4-(methoxymethyl)benzoate (CAS 227948-38-1)
- 1-Cyclopropyl-6-fluoro-7-(4-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 141874-19-3)
- Methyl 2-{[(3-methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-yliden)methyl]amino}acetate (CAS 159592-98-0)
- tert-Butyl 4-((4-chloropyrimidin-2-yl)(methyl)amino)piperidine-1-carboxylate (CAS 1261233-28-6)
- n-(4-Methylpentyl)thiophene-2-carboxamide (CAS 349097-53-6)
- 4-Amino-N-(3-(diethylamino)propyl)-7-fluorocinnoline-3-carboxamide (CAS 187231-57-8)
- 5-Chloro-3-nitro-1H-pyrazolo[4,3-d]pyrimidine (CAS 2173992-57-7)
- 1-(2-(5-Cyclopropyl-3-(pyridin-4-yl)-1H-pyrazol-1-yl)ethyl)-3-(thiophen-2-yl)urea (CAS 1797673-78-9)
- (R)-2-((tert-butoxycarbonyl)amino)-4-(3,5-difluorophenyl)butanoic acid (CAS 1260606-36-7)
- Semaglutide impurity 107 (CAS CATO-C4X-2226107)
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