4-{[1,1'-Biphenyl]-4-carbonyl}-8-tert-Butyl-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid CAS 1326809-75-9
| CAS No. | 1326809-75-9 |
| Molecular Formula | C26H31NO4 |
| Molecular Weight | 421.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-{[1,1'-Biphenyl]-4-carbonyl}-8-tert-Butyl-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid (CAS 1326809-75-9) is a high-purity analytical reference standard with the molecular formula C26H31NO4 and a molecular weight of 421.53 g/mol.
4-{[1,1'-Biphenyl]-4-carbonyl}-8-tert-Butyl-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid (C26H31NO4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H31NO4 |
| Molecular Weight | 421.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
Related Biphenyl Standards
- 1-{[1,1'-Biphenyl]-4-yl}-2-(3,5-dibromo-1H-1,2,4-triazol-1-yl)ethan-1-one (CAS 1240571-64-5)
- Tri([1,1'-biphenyl]-4-yl)methanol (CAS 5341-14-0)
- (R)-(4-([1,1'-Biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl)(2-benzylpiperidin-1-yl)methanone (CAS 2055172-60-4)
- (S)-(4-([1,1'-Biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl)(2-benzylpiperidin-1-yl)methanone (CAS 2055172-61-5)
- [1,1'-Biphenyl]-3-propanoic acid, α-amino-2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)-, (αS)- (CAS 174575-40-7)
- 2-([1,1'-Biphenyl]-3-yl)-4-([1,1'-biphenyl]-4-yl)-6-chloro-1,3,5-triazine (CAS 1621467-35-3)
- 2-([1,1'-Biphenyl]-2-yl)-4-([1,1'-biphenyl]-4-yl)-6-chloro-1,3,5-triazine (CAS 2279137-61-8)
- 2-([1,1'-Biphenyl]-4-yl)-4-(3-chlorophenyl)-6-phenyl-1,3,5-triazine (CAS 2085262-87-7)
Recommended Standards
- (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-(undecylamino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol (CAS 111863-54-8)
- 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-cyclooctylpropanoic acid (CAS 1379870-88-8)
- 5B38CV1212 1048668-70-7 AZD-8329 UNII-5B38CV1212 Benzoic acid, 4-(5-(1,1-dimethylethyl)-4-((tricyclo(3.3.1.13,7)dec-2-ylamino)carbonyl)-1H-pyrazol-1-yl)- 4-(4-(Adamant-2-ylcarbamoyl)-5-tert-butylpyrazol-1-yl)benzoic acid AZD 8329 (CAS 1048668-70-7)
- tert-Butyl 4-(2-hydroxy-1-(2-phenyl-1H-benzo[d]imidazol-1-yl)ethyl)piperidine-1-carboxylate (CAS 1440753-74-1)
- (11bR)-4-Phenoxy-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin (CAS 188055-47-2)
- 1-(2-Chlorophenyl)-5-(pyridin-3-yl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1031977-12-4)
- Methyl 5-fluoro-2-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxylate (CAS 1645-99-4)
- Phenyl-beta-D-thioglucuronic acid (CAS 26399-82-6)
- 4-Isopropylisobenzofuran-1,3-dione (CAS 54108-76-8)
- 2,3,5,6-Tetrafluoro-4-Iodo-Phenol (CAS 1998-58-9)
- Sulbactam EP Impurity E (CAS 76646-91-8)
- 5-[(1E)-1-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]hydrazin-1-ylidene}ethyl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 321432-20-6)
- 2-Amino-9-(furan-2-ylmethyl)-1H-purin-6(9H)-one (CAS 14937-74-7)
- Semaglutide impurity 55 (CAS CATO-C4X-222655)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com