8-Benzyl-4-(4-nitrobenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid CAS 1326809-86-2
| CAS No. | 1326809-86-2 |
| Molecular Formula | C22H23N3O6 |
| Molecular Weight | 425.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
8-Benzyl-4-(4-nitrobenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326809-86-2) is a high-purity analytical reference standard with the molecular formula C22H23N3O6 and a molecular weight of 425.43 g/mol.
The molecular framework of 8-Benzyl-4-(4-nitrobenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (C22H23N3O6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 8-Benzyl-4-(4-nitrobenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H23N3O6 |
| Molecular Weight | 425.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 3 |
Related Benzyl Standards
- 8-Benzyl-4-(3-nitrobenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326813-50-6)
- Ethyl 5-((3-nitrobenzoyl)oxy)-2-phenylbenzofuran-3-carboxylate (CAS 6240-53-5)
- Ethyl 5-((4-nitrobenzoyl)oxy)-2-phenylbenzofuran-3-carboxylate (CAS 6239-99-2)
- Ethyl 3-(3-nitrobenzoyl)-5-(pyridin-2-yl)indolizine-1-carboxylate (CAS 853317-40-5)
- Ethyl 3-(4-nitrobenzoyl)-5-(pyridin-2-yl)indolizine-1-carboxylate (CAS 252201-19-7)
- 3-(2-(4-(4-Nitrobenzoyl)piperidin-1-yl)ethyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one (CAS 139418-53-4)
- 1-(4-Nitrobenzoyl)-4-{5-[3-(trifluoromethyl)phenyl]-1H-pyrazol-3-yl}piperidine (CAS 1025724-70-2)
- 6-(4-Nitrobenzoyl)-5,6-dihydro-4H-benzo[b]thieno[2,3-d]azepine-2-carboxylic acid (CAS 200122-35-6)
Recommended Standards
- 7-(3-Amino-3-Phenylpyrrolidin-1-yl-1-Cyclopropyl-6,8-Difluoro-4-Oxoquinoline-3-Carboxylic Acid (CAS 116169-42-7)
- tert-Butyl 2'-(((trifluoromethyl)sulfonyl)oxy)-5',6'-dihydrospiro[piperidine-4,4'-pyrrolo[1,2-b]pyrazole]-1-carboxylate (CAS 2751664-13-6)
- 2-[[(5S)-2-oxo-3-[2,3,5,6-tetradeuterio-4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]isoindole-1,3-dione (CAS 1330180-09-0)
- N'-(1-(phenylsulfonyl)piperidin-4-ylidene)-3-(trifluoromethyl)benzohydrazide (CAS 478248-22-5)
- 3’-Bromo-4’-(1-pyrazolyl)acetophenone (CAS 1186663-58-0)
- 1-(3-O-Acetyl-2-deoxy-ß-D-erythro-pentofuranosyl)-4-amino-1,3,5-triazin-2(1H)-one (CAS 1254186-97-4)
- (4-Phenyl-1,2,3-thiadiazol-5-yl)methanol (CAS 423768-62-1)
- 1-(2,2,2-Trifluoroethyl)-1H-1,2,4-triazole (CAS 1340049-32-2)
- Tert-butyl 4-(3,5-dibromopyridin-2-yl)piperazine-1-carboxylate (CAS 1223432-03-8)
- 1,2-Bis(4-bromobenzoyl)hydrazine (CAS 69673-99-0)
- 5-Bromo-1-methoxyisoquinolin-4-amine (CAS 1781537-72-1)
- 5-(5-Fluoro-2-methoxyphenyl)-3-methyl-5-oxovaleric acid (CAS 951885-39-5)
- 3-Bromobenzofuran-2(3H)-one (CAS 115035-43-3)
- D-Gln24-Tirzepatide (CAS CATO-CPTD788910)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com