4-(2-Chlorobenzoyl)-8-methyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid CAS 1326810-13-2
| CAS No. | 1326810-13-2 |
| Molecular Formula | C16H19ClN2O4 |
| Molecular Weight | 338.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(2-Chlorobenzoyl)-8-methyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(2-Chlorobenzoyl)-8-methyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326810-13-2), molecular formula C16H19ClN2O4 and molecular weight 338.79 g/mol, is a CATO reference standard with documented purity and traceability.
4-(2-Chlorobenzoyl)-8-methyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (C16H19ClN2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(2-Chlorobenzoyl)-8-methyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H19ClN2O4 |
| Molecular Weight | 338.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorobenzoyl Standards
- 4-(3-Chlorobenzoyl)-8-methyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326808-39-2)
- 4-(4-Chlorobenzoyl)-N'-phenyl-1H-pyrrole-2-carbohydrazide (CAS 338403-36-4)
- N'-(3-chlorobenzoyl)-2-(1H-pyrrol-1-yl)benzohydrazide (CAS 478062-93-0)
- N'-(4-chlorobenzoyl)-2-(1H-pyrrol-1-yl)benzohydrazide (CAS 478063-00-2)
- 4-(4-Chlorobenzoyl)-8-methyl-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid (CAS 1009354-95-3)
- 4-(3-Chlorobenzoyl)-8-methyl-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid (CAS 1326810-90-5)
- 4-(2-Chlorobenzoyl)-8-methyl-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid (CAS 1326813-91-5)
- 2-(4-(2-Chlorobenzoyl)-1-methyl-5-(methylthio)-2-oxo-2,5-dihydro-1H-pyrrol-3-yl)acetic acid (CAS 1269534-86-2)
Recommended Standards
- 1-(4-Chlorophenyl)-3-(4-phenoxyphenyl)urea (CAS 167634-42-6)
- 4-Chloro-2-(4-isopropoxyphenyl)benzofuro[3,2-d]pyrimidine (CAS 1315326-77-2)
- 1-(3-Chlorophenyl)-3-(4-phenoxyphenyl)urea (CAS 178607-15-3)
- 2-((Tert-butoxycarbonyl)amino)-3-(4-chloro-1H-indol-3-yl)propanoic acid (CAS 1313033-19-0)
- (R)-2-(3-(N-Methylacetamido)pyrrolidin-1-yl)acetic acid (CAS 1354018-10-2)
- 1-Boc-3-(1-phenylethylamino)-4-piperidinemethanol (CAS 1305320-69-7)
- Methyl 3,5-dichloro-4-propoxybenzoate (CAS 1368285-65-7)
- (2E)-3-[(2,4-Dimethoxyphenyl)amino]-2-(thiophen-3-yl)prop-2-enenitrile (CAS 477851-19-7)
- (2R,3R,4S,5S)-2-(acetoxymethyl)-6-hydroxytetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS 58645-20-8)
- 1-(3,4-Dinitro-1H-pyrazol-1-yl)propan-2-one (CAS 131394-09-7)
- (3R,4S)-4-Amino-3-methoxytetrahydropyran (CAS 1421066-70-7)
- Allyl 4-(2-(methylamino)ethyl)piperazine-1-carboxylate (CAS 886365-67-9)
- 4-(Methylthio)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 70011-68-6)
- Semaglutide impurity 200 (CAS CATO-C4X-2226200)
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