4-(Naphthalene-2-carbonyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid CAS 1326811-05-5
| CAS No. | 1326811-05-5 |
| Molecular Formula | C22H26N2O4 |
| Molecular Weight | 382.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(Naphthalene-2-carbonyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid.
4-(Naphthalene-2-carbonyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326811-05-5) is a high-purity analytical reference standard with the molecular formula C22H26N2O4 and a molecular weight of 382.45 g/mol.
The molecular framework of 4-(Naphthalene-2-carbonyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (C22H26N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H26N2O4 |
| Molecular Weight | 382.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
Related Naphthalene Standards
- 4-(Naphthalene-1-carbonyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326809-67-9)
- 4-[4-(naphthalene-2-sulfonyl)piperazin-1-yl]-4-oxobutanoic acid (CAS 554442-47-6)
- Naphthalene-1,3,5-trisulfonic acid, sodium salt(1:1) (CAS 104768-26-5)
- n'-(Naphthalene-2-sulfonyl)-1,3-dioxaindane-5-carbohydrazide (CAS 930532-29-9)
- 2,2'-(Naphthalene-1,5-diylbis(oxy))bis(1-phenylethan-1-one) (CAS 319482-15-0)
- 8-Ethyl-4-(naphthalene-1-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326809-47-5)
- 8-Ethyl-4-(naphthalene-2-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326811-85-1)
- 3,3'-(Naphthalene-2,7-diyl)dibenzoic acid (CAS 1426343-41-0)
Recommended Standards
- N-(4-Methoxyphenyl)-2-methyl-6-(p-tolyl)quinoline-3-carboxamide (CAS 1426813-86-6)
- Paulownin (CAS 13040-46-5)
- (4R,4′R)-2,2′-(Phenylmethylene)bis[4,5-dihydro-4-phenyloxazole] (CAS 1442644-11-2)
- (R)-2-((tert-butoxycarbonyl)amino)-4-((1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl)amino)butanoic acid (CAS 1263046-41-8)
- 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-3-(2,6-dichlorophenyl)thiourea (CAS 326815-32-1)
- 4-(2-Bromoethyl)morpholine hydrochloride (CAS 89583-06-2)
- 1-((3-(Diethylamino)-2-hydroxypropyl)amino)-4-((oxiran-2-ylmethyl)amino)anthracene-9,10-dione fumarate (CAS 144181-12-4)
- [2,3'-Biquinoline]-2'-carbonitrile (CAS 62737-95-5)
- 7-Chloro-9-methoxy-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine (CAS 1708370-83-5)
- (S)-N-(1-(4-Bromophenyl)-2,2,2-trifluoroethyl)methanesulfonamide (CAS 1448682-01-6)
- (S)-2-(((Benzyloxy)carbonyl)amino)-3-mercaptopropanoic acid (CAS 156916-81-3)
- 1-Cyclopentyl-3-methyl-1h-pyrazole-5-sulfonyl chloride (CAS 1245806-72-7)
- N1-(Benzo[d][1,3]dioxol-5-ylmethyl)-N2-(isoxazol-3-yl)oxalamide (CAS 941980-40-1)
- FMRF Amide Related Peptide. (CAS 149471-12-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com