4-(4-Chloro-3-nitrobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid CAS 1326812-66-1
| CAS No. | 1326812-66-1 |
| Molecular Formula | C18H22ClN3O6 |
| Molecular Weight | 411.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(4-Chloro-3-nitrobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326812-66-1), molecular formula C18H22ClN3O6 and molecular weight 411.84 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-(4-Chloro-3-nitrobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (C18H22ClN3O6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 411.84 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H22ClN3O6 |
| Molecular Weight | 411.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 4-(2-Chloro-5-nitrobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326810-16-5)
- 2-((1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-imidazol-2-yl)thio)-1-(p-tolyl)ethan-1-one (CAS 303988-47-8)
- (2E)-1-{3-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-3-[(4-methoxyphenyl)amino]prop-2-en-1-one (CAS 478039-46-2)
- (2E)-1-{4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-3-[(4-methoxyphenyl)amino]prop-2-en-1-one (CAS 477871-15-1)
- (2E)-3-{4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-N-(4-methoxyphenyl)prop-2-enamide (CAS 477870-77-2)
- 1-(5-Chloro-2-nitrobenzenesulfonyl)-4-(2-methoxyphenyl)piperazine (CAS 866153-18-6)
- 4-Chloro-N-(4-(quinoxalin-2-yloxy)phenyl)benzenesulfonamide (CAS 400080-03-7)
- 4-Chloro-N-[(4E)-2-oxo-3-phenyl-1,2,3,4-tetrahydroquinazolin-4-ylidene]benzene-1-sulfonamide (CAS 478044-04-1)
Recommended Standards
- (4-(5-Bromo-2-chlorobenzyl)phenoxy)(tert-butyl)dimethylsilane (CAS 864070-19-9)
- Sitafloxacin Impurity 28 (CAS CATO-C4X-115528)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-chloro-1H-pyrazol-1-yl)propanoic acid (CAS 2137517-20-3)
- N-(2-Chlorophenyl)-3-{[3-(trifluoromethyl)phenyl]methoxy}thiophene-2-carboxamide (CAS 344273-18-3)
- 6-[(2E)-2-{[(4-chlorophenyl)methoxy]imino}ethyl]-1-[2-(3,4-dimethoxyphenyl)ethyl]-4-oxo-1,4-dihydropyrimidine-5-carbonitrile (CAS 303148-52-9)
- 2-(6,7-Dihydro-1H-[1,4]dioxino[2',3':4,5]benzo[1,2-d]imidazol-2-yl)ethan-1-amine (CAS 933705-16-9)
- (E)-N-{1-[5-(4-fluorophenyl)thiophen-2-yl]ethylidene}hydroxylamine (CAS 1118787-05-5)
- Ezetimibe Impurity 73 (CAS 845790-38-7)
- 5,5'-(Furan-2-ylmethylene)bis(2-methylfuran) (CAS 59212-78-1)
- 1-Ethyl-N-isobutyl-3-isopropyl-1h-pyrazole-5-carboxamide (CAS 1209101-53-0)
- 2-(4-Bromophenyl)-5-methyl-2,5-diazabicyclo[2.2.1]heptane (CAS 1780761-67-2)
- 2,6-Bis(trifluoromethyl)benzyl alcohol (CAS 152211-16-0)
- Cimiracemoside C (CAS 256925-92-5)
- endo-Gly31-Semaglutide (CAS CATO-C4X-2226282)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com