3-(4-Bromo-2-fluorophenyl)-5-methyl-4,5-dihydro-1,2-oxazole-5-carboxylic acid CAS 1326814-83-8
| CAS No. | 1326814-83-8 |
| Molecular Formula | C11H9BrFNO3 |
| Molecular Weight | 302.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(4-Bromo-2-fluorophenyl)-5-methyl-4,5-dihydro-1,2-oxazole-5-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(4-Bromo-2-fluorophenyl)-5-methyl-4,5-dihydro-1,2-oxazole-5-carboxylic acid (CAS 1326814-83-8) is a high-purity analytical reference standard with the molecular formula C11H9BrFNO3 and a molecular weight of 302.10 g/mol.
The molecular framework of 3-(4-Bromo-2-fluorophenyl)-5-methyl-4,5-dihydro-1,2-oxazole-5-carboxylic acid (C11H9BrFNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(4-Bromo-2-fluorophenyl)-5-methyl-4,5-dihydro-1,2-oxazole-5-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H9BrFNO3 |
| Molecular Weight | 302.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 1-(4-Bromo-2-fluorophenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 1016697-56-5)
- 3-(5-Bromo-2-fluorophenyl)-5-methyl-4,5-dihydro-1,2-oxazole-5-carboxylic acid (CAS 1326814-80-5)
- 2-Bromo-5-(3-nitrophenoxy)-1,3,4-thiadiazole (CAS 1339381-69-9)
- 2-Bromo-5-(4-nitrophenoxy)-1,3,4-thiadiazole (CAS 1343454-17-0)
- (2-Bromo-5-(trifluoromethyl)phenyl)(imino)(methyl)-l6-sulfanone (CAS 2966063-86-3)
- (3-Bromo-5-(trifluoromethyl)phenyl)(imino)(methyl)-l6-sulfanone (CAS 2923307-03-1)
- (4-Bromo-2-(trifluoromethyl)phenyl)(imino)(methyl)-l6-sulfanone (CAS 2966063-85-2)
- 1-(5-Bromo-6-(methylthio)pyridin-3-yl)-2,2,2-trifluoroethan-1-ol (CAS 2791313-09-0)
Recommended Standards
- 4,4,5,5-Tetramethyl-2-(2-methyl-4-(trifluoromethoxy)phenyl)-1,3,2-dioxaborolane (CAS 1309980-29-7)
- Dimethyl 1,1'-ferrocenedicarboxylate (CAS 1273-95-6)
- 2-(3-Methoxy-4-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1421341-06-1)
- N-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)pyridin-2-amine (CAS 1257431-67-6)
- 5-(2-Cyclobutylethyl)-3-methylisoxazole (CAS 921588-37-6)
- (R)-3-(1-Aminobutyl)benzonitrile hydrochloride (CAS 1212968-03-0)
- 1-(4,5-Dihydro-1H-imidazol-2-yl)ethan-1-ol (CAS 91144-41-1)
- 2-Bromo-4-(trifluoromethyl)thiazole-5-carbonitrile (CAS 1823869-30-2)
- 2-(1-(Dimethylcarbamoyl)pyridin-1-ium-4-yl)ethane-1-sulfonate (CAS 136997-71-2)
- Ethyl 4-(3-bromo-4-methylphenyl)-4-oxobutanoate (CAS 898776-82-4)
- 5-Cyclopropoxy-2-iodo-3-isopropylpyridine (CAS 1243375-82-7)
- 2-Chloro-4-methanesulfonyl-N-{4-[3-(trifluoromethyl)benzenesulfonyl]phenyl}benzamide (CAS 339105-03-2)
- Pramipexole Impurity 46 (CAS 104617-49-4)
- Semaglutide impurity 67 (CAS CATO-C4X-222667)
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