Ethyl 3-amino-1-(2,2-difluoroethyl)-1H-pyrazole-5-carboxylate CAS 1328640-74-9
| CAS No. | 1328640-74-9 |
| Molecular Formula | C8H11F2N3O2 |
| Molecular Weight | 219.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 3-amino-1-(2,2-difluoroethyl)-1H-pyrazole-5-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ethyl 3-amino-1-(2,2-difluoroethyl)-1H-pyrazole-5-carboxylate (CAS 1328640-74-9) is a high-purity analytical reference standard with the molecular formula C8H11F2N3O2 and a molecular weight of 219.19 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Ethyl 3-amino-1-(2,2-difluoroethyl)-1H-pyrazole-5-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 219.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Ethyl 3-amino-1-(2,2-difluoroethyl)-1H-pyrazole-5-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H11F2N3O2 |
| Molecular Weight | 219.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- Methyl 8-amino-4-oxo-4H-chromene-3-carboxylate (CAS 1253654-50-0)
- Methyl 6-amino-4-oxo-4H-chromene-2-carboxylate (CAS 128852-81-3)
- 5-Amino-3-(2,2-difluoroethyl)-1-ethylpyrimidine-2,4(1h,3h)-dione (CAS 1342578-43-1)
- Ethyl 3-amino-1-(2,2-difluoroethyl)-1H-pyrazole-4-carboxylate (CAS 1791389-44-0)
- 2-Amino-6-methoxy-4-oxo-4H-1-benzopyran-3-carboxaldehyde (CAS 68301-78-0)
- 1-(6-Amino-5-nitro-1H-indol-1-yl)ethanone (CAS 1000343-09-8)
- 5-Amino-3-(3-methyl-2-nitrophenyl)-1H-1,2,4-triazole (CAS 1016750-18-7)
- Methyl 5-amino-1-(pyrimidin-2-yl)-1H-pyrazole-4-carboxylate (CAS 104909-69-5)
Recommended Standards
- 3-Acetoxy-1h-indole-5-carboxylic acid (CAS 1306603-15-5)
- 3-(2,4-Difluorobenzoyl)pyridine (CAS 133385-30-5)
- 1-(Carboxymethyl)-1h-indole-2-carboxylic acid (CAS 126718-55-6)
- 5-(3,4-Difluorophenyl)nicotinaldehyde (CAS 1346691-73-3)
- 1-(2-Methoxyethyl)-1H-pyrazole-5-carbaldehyde (CAS 1352519-93-7)
- 2-(Pyridin-2-yl)piperazine (CAS 111759-97-8)
- 3-(2-chloropropyl)-4,5-dimethoxybenzoic acid (CAS 877964-62-0)
- 5-(Benzyloxy)-2-fluoro-3-(trifluoromethyl)phenylboronic acid (CAS 2096331-25-6)
- 4-(5-Bromo[1,3,4]thiadiazol-2-yl)morpholine (CAS 1341405-19-3)
- 2-((4-Methoxy-3-phenylquinolin-2-yl)thio)-N,N-dimethylethanamine (CAS 89081-07-2)
- 2-[[4-[[4-[(2,4-Diaminopteridin-6-ylMethyl-Methylamino]Benzoyl]Amino]-2-Fluoro-5-Hydroxy-5-Oxopentanoyl]Amino]Pentanedioic Acid (CAS 124716-15-0)
- 2-Ethyl-1H-naphtho[1,2-d]imidazole (CAS 24142-40-3)
- 2-(6-Bromo-3-(trifluoromethyl)pyridin-2-yl)acetic acid (CAS 1805029-89-3)
- Semaglutide Impurity 183 (CAS 159541-28-3)
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