N,N-Dimethyl-N-[2-(trifluoromethoxy)benzyl]-ethane-1,2-diamine dihydrochloride CAS 1328641-59-3
| CAS No. | 1328641-59-3 |
| Molecular Formula | C12H17F3N2O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N,N-Dimethyl-N-[2-(trifluoromethoxy)benzyl]-ethane-1,2-diamine dihydrochloride (C12H17F3N2OHCl) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
N,N-Dimethyl-N-[2-(trifluoromethoxy)benzyl]-ethane-1,2-diamine dihydrochloride (CAS 1328641-59-3) is a high-purity analytical reference standard with the molecular formula C12H17F3N2OHCl and a molecular weight of 298.73 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N,N-Dimethyl-N-[2-(trifluoromethoxy)benzyl]-ethane-1,2-diamine dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H17F3N2O 2*HCl |
| Molecular Weight | 298.73 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- N1-(Benzo[d][1,3]dioxol-5-yl)-N2-cyclopropyloxalamide (CAS 701223-32-7)
- 5-Amino-1-(3-chlorophenyl)-1H-pyrazole-4-carboxamide (CAS 50427-78-6)
- 3-amino-6-(dimethylamino)-2,3-dihydro-1H-indol-2-one dihydrochloride (CAS 1786215-06-2)
- 17(Z)-Hexacosenoic Acid (CAS 66274-43-9)
- 4-(3-Fluorobicyclo[1.1.1]Pentan-1-yl)benzoic acid (CAS 1980053-59-5)
- 2,2,2-Trifluoroethyl 2-(4-methylpiperazin-1-yl)ethane-1-sulfonate dioxalate (CAS 353744-64-6)
- Albendazole EP Impurity D (CAS 80983-34-2)
- Ethyl 4-(tert-butyl)-3-iodobenzoate (CAS 92039-18-4)
- (R)-Ketoprofen β-D-glucuronide (CAS 140148-25-0)
- Semaglutide impurity 40 (CAS CATO-C4X-222640)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com