2-(2-Fluorophenoxy)ethanesulfonyl chloride CAS 1330752-42-5
| CAS No. | 1330752-42-5 |
| Molecular Formula | C8H8ClFO3S |
| Molecular Weight | 238.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(2-Fluorophenoxy)ethanesulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2-(2-Fluorophenoxy)ethanesulfonyl chloride (CAS 1330752-42-5), a certified reference material (molecular formula C8H8ClFO3S, MW 238.66 g/mol) for analytical method development and quality control.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 2-(2-Fluorophenoxy)ethanesulfonyl chloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 238.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H8ClFO3S |
| Molecular Weight | 238.66 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Fluorophenoxy Standards
- 2-(4-Fluorophenoxy)ethanesulfonyl chloride (CAS 1018548-27-0)
- 1-[2-(4-Fluorophenoxy)ethyl]-2-methylpiperazine (CAS 1240571-12-3)
- 1-(3-(4-Fluorophenoxy)propyl)piperazine (CAS 91940-44-2)
- 1-[2-(4-Fluorophenoxy)ethyl]-1,4-diazepane (CAS 944086-63-9)
- 2-(4-Fluorophenoxy)-1-(piperazin-1-yl)ethan-1-one (CAS 256943-72-3)
- 1-(4-Fluorophenoxy)cyclohexanecarboxylic acid (CAS 1267028-24-9)
- 1-(2-(4-Fluorophenoxy)ethyl)azetidine-3-carboxylic acid (CAS 1408104-55-1)
- 5-[(4-Fluorophenoxy)methyl]-4-methyl-4H-1,2,4-triazole-3-thiol 667437-43-6 7774AE C10H10FN3OS (CAS 667437-43-6)
Recommended Standards
- 4-(Chloromethyl)-2,4'-difluoro-1,1'-biphenyl (CAS 1214340-98-3)
- 6,6,6-Trifluorohexane-1-sulfonyl chloride (CAS 1349708-68-4)
- (3-Fluoro-4-methoxyphenyl)methanesulfonyl chloride (CAS 1178706-94-9)
- 3-Fluoro-4-methoxy-2-methylbenzenesulfonyl chloride (CAS 1461705-63-4)
- 2-(Methoxymethyl)pyrazolo[1,5-a]pyridine (CAS 685886-56-0)
- 4-((3aS,4R,9bR)-6-Ethoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl)benzoic acid (CAS 1357248-83-9)
- 3,4-Dimethylbenzene-1,2-diamine (CAS 41927-01-9)
- (R)-3-((tert-butoxycarbonyl)amino)-2,3-dihydro-1H-indene-5-carboxylic acid (CAS 1365157-31-8)
- 444989-46-2 3-Chloro-4-(tributylstannyl)-pyridine MFCD22370076 (CAS 444989-46-2)
- 5-Fluoro-2-(1-(isobutylamino)ethyl)phenol (CAS 1310270-33-7)
- 2-((4-Methyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetic acid (CAS 338425-50-6)
- Irinotecan Impurity 62 (CAS CATO-C4X-166762)
- 2-(5-Methoxy-1,2-benzoxazol-3-yl)acetic acid (CAS 34172-98-0)
- Peptide Impurity 70 TFA Salt (CAS CATO-CPTD788570)
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