5-Chloro-3-iodo-8-methylquinolin-4(1H)-one CAS 1330754-67-0
| CAS No. | 1330754-67-0 |
| Molecular Formula | C10H7ClINO |
| Molecular Weight | 319.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-3-iodo-8-methylquinolin-4(1H)-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-Chloro-3-iodo-8-methylquinolin-4(1H)-one (CAS 1330754-67-0), a certified reference material (molecular formula C10H7ClINO, MW 319.53 g/mol) for analytical method development and quality control.
The molecular framework of 5-Chloro-3-iodo-8-methylquinolin-4(1H)-one (C10H7ClINO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Chloro-3-iodo-8-methylquinolin-4(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7ClINO |
| Molecular Weight | 319.53 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-Chloro-3-iodo-6-methoxyquinoline (CAS 1190972-42-9)
- 4-Chloro-7-iodo-6-methoxyquinoline (CAS 1268520-28-0)
- 6-Chloro-3-iodo-8-methylquinolin-4(1H)-one (CAS 1330752-77-6)
- 7-Chloro-3-iodo-2-methylquinolin-4(1H)-one (CAS 1330753-24-6)
- 7-Chloro-3-iodo-8-methylquinolin-4(1H)-one (CAS 1330755-21-9)
- 5-Chloro-7-iodo-8-methoxyquinoline (CAS 91240-91-4)
- N-(5-chloro-2-fluoro-4-iodo-phenyl)acetamide (CAS 2157481-37-1)
- 4-Chloro-2-(3,5-dichlorophenyl)-5-(1-methylhydrazino)-2,3-dihydropyridazin-3-one (CAS 175135-84-9)
Recommended Standards
- 5-(Nonylthio)quinoline-8-thiol (CAS 60465-71-6)
- Ethyl (3-bromo-6-chloroimidazo[1,2-b]pyridazin-2-yl)carbamate (CAS 1172470-59-5)
- 4-(chloromethyl)-2-(4-iodophenyl)-1,3-oxazole (CAS 1179743-32-8)
- Ethyl (8-bromo-5-chloro-[1,2,4]triazolo[4,3-a]pyridin-3-yl)carbamate (CAS 1626336-60-4)
- 9-Benzyl 4-(tert-butyl) 1,4,9-triazaspiro[5.6]Dodecane-4,9-dicarboxylate (CAS 1639963-94-2)
- 1-(2-Bromophenyl)-5-methyl-3-(trifluoromethyl)-1H-pyrazole (CAS 927388-16-7)
- N-(2-(2,5-Dichlorophenyl)-5-phenyl-2H-1,2,3-triazol-4-yl)benzamide (CAS 830336-16-8)
- 4-Hydroxy nitrofurantoin (CAS 76644-41-2)
- 3,3,3-Trifluoro-2-(2-methoxy-5-methylphenyl)propan-1-amine (CAS 1514300-29-8)
- 3-Chloro-1-ethyl-5,6,7,8-tetrahydroisoquinoline-4-carboxamide (CAS 361534-80-7)
- 1-Isopentyl-1H-pyrido[2,3-d][1,3]oxazine-2,4-dione (CAS 565448-79-5)
- Mesalazine EP Impurity L (CAS 118-91-2)
- Paricalcitol Impurity 4 (CAS 2230789-87-2)
- Myristoyl Pentapeptide-4 (CAS 1392416-25-9)
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