Betacarotene EP Impurity D CAS 13312-52-2
| CAS No. | 13312-52-2 |
| Molecular Formula | C40H56 |
| Molecular Weight | 536.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Betacarotene EP Impurity D.
CATO supplies Betacarotene EP Impurity D (CAS 13312-52-2), a pharmacopoeial impurity reference standard (molecular formula C40H56, MW 536.87 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Betacarotene EP Impurity D (C40H56) is characterized by a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C40H56 |
| Molecular Weight | 536.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | Technical Grade |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
Related Betacarotene Standards
- Betacarotene EP Impurity B (CAS 472-93-5)
- Betacarotene EP Impurity C (CAS CATO-C4X-28153)
- Betacarotene EP Impurity E (CAS 6811-73-0)
- Betacarotene EP Impurity F (CAS 19361-58-1)
- Betacarotene impurity 12 (CAS CATO-C4X-281512)
- Betacarotene impurity 13 (CAS CATO-C4X-281513)
- Betacarotene impurity 7 (CAS CATO-C4X-28157)
- Betacarotene impurity 10 (CAS CATO-C4X-281510)
Recommended Standards
- (9-cis,15-cis)-β,β-Carotene (CAS 51364-07-9)
- Beta-Carotene (CAS 7235-40-7)
- Alpha-Carotene (CAS 432-70-2)
- alpha-Carotene (CAS 7488-99-5)
- Regorafenib Impurity 63 (CAS CATO-C4X-104763)
- Esmolol Impurity 95 (CAS CATO-C4X-189195)
- Esmolol Impurity 85 (CAS CATO-C4X-189185)
- N-Methyl-5-(trifluoromethyl)-2-pyridinamine (CAS 937602-15-8)
- N-(2-(2-Methyl-1H-imidazol-1-yl)pyrimidin-5-yl)furan-2-carboxamide (CAS 1421493-80-2)
- 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(naphthalen-1-yl)urea (CAS 1024165-54-5)
- 1452577-32-0 1-[3-(Trifluoromethyl)phenyl]-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid acetate MFCD27756430 (CAS 1452577-32-0)
- 6-Methoxy-7-propoxyisoquinoline (CAS 67625-58-5)
- 5-Bromopyrazin-2-yl acetate (CAS 1209459-60-8)
- Endo-Pro36-Tirzepatide (CAS CATO-CPTD788688)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com