(E)-N-(2-(2-Methyl-1H-imidazol-1-yl)ethyl)-3-(thiophen-2-yl)acrylamide CAS 1331448-65-7
| CAS No. | 1331448-65-7 |
| Molecular Formula | C13H15N3OS |
| Molecular Weight | 261.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (E)-N-(2-(2-Methyl-1H-imidazol-1-yl)ethyl)-3-(thiophen-2-yl)acrylamide (C13H15N3OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
(E)-N-(2-(2-Methyl-1H-imidazol-1-yl)ethyl)-3-(thiophen-2-yl)acrylamide (CAS 1331448-65-7) is a high-purity analytical reference standard with the molecular formula C13H15N3OS and a molecular weight of 261.34 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (E)-N-(2-(2-Methyl-1H-imidazol-1-yl)ethyl)-3-(thiophen-2-yl)acrylamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H15N3OS |
| Molecular Weight | 261.34 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Recommended Standards
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- 2-Chloro-4-methoxy-3,5-dimethylpyridine (CAS 110464-98-7)
- 1-(2-Bromo-ethoxy)-1,1,2,2,2-pentafluoro-ethane (CAS 1301738-96-4)
- Fulvestrant impurity 32 (CAS CATO-C4X-191732)
- rac-Clopidogrel-d3 Sulfate (CAS CATO-C4X-102922)
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- Semaglutide impurity 83 (CAS CATO-C4X-222683)
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