6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine monohydrochloride CAS 133277-08-4
| CAS No. | 133277-08-4 |
| Molecular Formula | C10H12BrN |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine monohydrochloride (C10H12BrNHCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine monohydrochloride (CAS 133277-08-4), a certified reference material (molecular formula C10H12BrNHCl, MW 262.57 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine monohydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12BrN HCl |
| Molecular Weight | 262.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- (S)-1-(3-Bromopyridin-4-yl)ethan-1-amine dihydrochloride (CAS 2089245-92-9)
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- 2-(Pentan-2-yloxy)aniline (CAS 27125-86-6)
- N-(furan-3-ylmethyl)thietan-3-amine (CAS 1849264-44-3)
- 2-(7,7-Dimethylbicyclo[2.2.1]heptan-1-yl)ethan-1-amine hydrochloride (CAS 63854-63-7)
- 4-Chloro-6-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline (CAS 1256784-33-4)
- 4-(Cyclohexyloxy)-3-hydroxybenzamide (CAS 1243451-37-7)
- isopropyl (Z)-3-iodoprop-2-enoate (CAS 1333154-26-9)
- Semaglutide Impurity 177 (CAS CATO-C4X-2226177)
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