5-chloro-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]aniline CAS 133303-68-1

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-chloro-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]aniline.

CATO supplies 5-chloro-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]aniline (CAS 133303-68-1), a certified reference material (molecular formula C10H10ClN3S, MW 239.72 g/mol) for analytical method development and quality control.

5-chloro-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]aniline (C10H10ClN3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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