(Z)-isopropyl 3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylate CAS 1333152-22-9
| CAS No. | 1333152-22-9 |
| Molecular Formula | C16H13F6N3O2 |
| Molecular Weight | 393.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (Z)-isopropyl 3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (Z)-isopropyl 3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylate (CAS 1333152-22-9), a certified reference material (molecular formula C16H13F6N3O2, MW 393.28 g/mol) for analytical method development and quality control.
The molecular framework of (Z)-isopropyl 3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylate (C16H13F6N3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (Z)-isopropyl 3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H13F6N3O2 |
| Molecular Weight | 393.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Z Standards
- Isopropyl (E)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylate (CAS 1421923-95-6)
- Isopropyl 2-amino-4-(3,4-difluorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate (CAS 924849-61-6)
- Isopropyl 2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)nicotinate (CAS 400086-51-3)
- Benzyl isopropyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate (CAS 1256360-23-2)
- 4-Isopropyl-N-(2-phenyl-1H-indol-5-yl)benzenesulfonamide (CAS 919490-48-5)
- 16-Isopropyl-2,2,15-trimethyl-4,14-dioxo-3,8,11-trioxa-5,15-diazaheptadecan-17-oic acid (CAS 1415807-25-8)
- 5-Isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo-[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (CAS 651744-16-0)
- 3-Isopropyl-1,4-bis(4-methoxybenzyl)piperazine-2,5-dione (CAS 479681-55-5)
Recommended Standards
- Benzyl (1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropyl)carbamate (CAS 1256359-24-6)
- 2-(Pyrazine-2-carboxamido)-N-(4-(trifluoromethoxy)phenyl)oxazole-4-carboxamide (CAS 1396793-35-3)
- Benzyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate (CAS 1020174-05-3)
- tert-Butyl (3-(benzyloxy)-6-bromo-2-methylpyridin-4-yl)carbamate (CAS 2796280-05-0)
- 4-(1-Methylethyl)-2,6-piperidinedione (CAS 98426-20-1)
- 4-methanesulfonyl-2,6-dinitrophenol (CAS 53559-50-5)
- n1-(Sec-butyl)-n2,n2-diisopropylethane-1,2-diamine (CAS 1019517-72-6)
- (E)-3-oxo-3-(p-tolyl)propanal O-methyl oxime (CAS 477851-40-4)
- 1-(3-Methyl-4-nitrophenyl)ethan-1-one (CAS 96784-58-6)
- (3AR,6aR)-4-acetylhexahydro-2H-furo[3,2-b]pyrrol-2-one (CAS 107690-56-2)
- tert-Butyl (S)-2-(((2-nitropyridin-3-yl)oxy)methyl)azetidine-1-carboxylate (CAS 209530-92-7)
- [(2R,3S)-2-(2-methylpyrazol-3-yl)tetrahydrofuran-3-yl]methanamine (CAS 1808535-99-0)
- N-(4-Aminopiperazin-1-yl)-2-chlorobenzamide (CAS 802861-41-2)
- Semaglutide Impurity 143 (CAS CATO-C4X-2226143)
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