2-(4-Chloro-3-fluorophenyl)-1-(2-methoxyethyl)-5-oxopyrrolidine-3-carboxylic acid CAS 1333577-80-2
| CAS No. | 1333577-80-2 |
| Molecular Formula | C14H15ClFNO4 |
| Molecular Weight | 315.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(4-Chloro-3-fluorophenyl)-1-(2-methoxyethyl)-5-oxopyrrolidine-3-carboxylic acid (C14H15ClFNO4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 2-(4-Chloro-3-fluorophenyl)-1-(2-methoxyethyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 1333577-80-2), a certified reference material (molecular formula C14H15ClFNO4, MW 315.72 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(4-Chloro-3-fluorophenyl)-1-(2-methoxyethyl)-5-oxopyrrolidine-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H15ClFNO4 |
| Molecular Weight | 315.72 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- Efavirenz 2-Desoxo-2-methly (CAS 1258498-53-1)
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- N-(2-((2-hydroxyethyl)amino)-2-oxoethyl)-4-methoxybenzamide (CAS 338396-48-8)
- Ethyl 2-{4-bromo-2-methoxy-6-[(1Z)-[(4-methylphenyl)imino]methyl]phenoxy}acetate (CAS 338750-65-5)
- 2-((6-Nitro-1,1-dioxido-2,3-dihydrobenzo[b]thiophen-3-yl)thio)acetohydrazide (CAS 685120-05-2)
- Ethyl 6-cyano-3-methoxy-1-methyl-2-oxo-1,2-dihydropyridine-4-carboxylate (CAS 1429204-82-9)
- 2-(5-Methylthiophen-2-yl)propan-2-ol (CAS 1443354-67-3)
- n-(Cyclopropylmethyl)-1-(o-tolyl)ethan-1-amine (CAS 1019539-69-5)
- Endo-38a-Pro-Exenatide trifluoroacetate salt (CAS 1678416-95-9)
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