6-(3-Chlorophenyl)-5-(hydroxymethyl)-1-methylpiperidin-2-one CAS 1333852-76-8
| CAS No. | 1333852-76-8 |
| Molecular Formula | C13H16ClNO2 |
| Molecular Weight | 253.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-(3-Chlorophenyl)-5-(hydroxymethyl)-1-methylpiperidin-2-one (CAS 1333852-76-8), molecular formula C13H16ClNO2 and molecular weight 253.72 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C13H16ClNO2, 6-(3-Chlorophenyl)-5-(hydroxymethyl)-1-methylpiperidin-2-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 253.72 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-(3-Chlorophenyl)-5-(hydroxymethyl)-1-methylpiperidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H16ClNO2 |
| Molecular Weight | 253.72 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenyl Standards
- 1-((4-Chlorophenyl)amino)cyclohexane-1-carboxylic acid (CAS 100380-25-4)
- Methyl 2-(2-(4-chlorophenyl)pyrrolidin-1-yl)acetate (CAS 1018127-45-1)
- 1-(4-Chlorophenyl)-2-(3-Hydroxypiperidin-1-Yl)Ethan-1-One (CAS 1146080-72-9)
- 2-(4-Chlorophenyl)-1-(3-hydroxypiperidin-1-yl)ethan-1-one (CAS 1153231-73-2)
- ethyl 2-(4-chlorophenyl)-2-(cyclopropylamino)acetate (CAS 1218642-88-6)
- 2-(4-Chlorophenyl)-1-(3-(hydroxymethyl)pyrrolidin-1-yl)ethan-1-one (CAS 1271071-41-0)
- 2-(3-Chlorophenyl)-1-methylpiperidine-3-carboxylic acid (CAS 1315367-70-4)
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Recommended Standards
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- tert-Butyl 4-chloroindoline-1-carboxylate (CAS 1337533-80-8)
- 3-Chloro-N-((3,4-dihydro-2h-pyran-2-yl)methyl)-4-methoxyaniline (CAS 1271670-30-4)
- 5-Bromo-2-thiophenesulfinic acid, sodium salt (CAS 126715-04-6)
- 1-(Chloromethyl)-2-methoxy-3-nitrobenzene (CAS 256455-93-3)
- Cyclohexene-1-boronic acid pinacol ester (CAS 141091-37-4)
- 4-Bromo-1-(tetrahydro-2H-pyran-2-yl)-5-(trifluoromethyl)-1H-indazole (CAS 2044704-81-4)
- N-[(4-Chlorophenyl)(Difluoro)Methyl]Cyclopropanamine (CAS 60010-38-0)
- 4-(Morpholinosulfonyl)benzaldehyde (CAS 77547-10-5)
- 3-(Difluoromethyl)-5-((4-methoxy-2-nitrophenyl)thio)-4H-1,2,4-triazole (CAS 1706450-48-7)
- 5,6-Dimethoxy-1H-indazole-3-carbonitrile (CAS 29281-09-2)
- 4-(4-Chlorophenyl)-6-methyl-N-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide (CAS 182170-95-2)
- (Des-Bromo)-Neuropeptide B (1-23) (human) (CAS 434897-64-0)
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