1-(4-Methylbenzyl)-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-sulfonyl chloride CAS 1334147-61-3
| CAS No. | 1334147-61-3 |
| Molecular Formula | C15H12ClN3O4S |
| Molecular Weight | 365.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-(4-Methylbenzyl)-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-sulfonyl chloride (CAS 1334147-61-3), a certified reference material (molecular formula C15H12ClN3O4S, MW 365.79 g/mol) for analytical method development and quality control.
1-(4-Methylbenzyl)-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-sulfonyl chloride (C15H12ClN3O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H12ClN3O4S |
| Molecular Weight | 365.79 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methylbenzyl Standards
- 3-(4-Methylbenzyl)-5-phenyl-3H-imidazo[4,5-c][1,8]naphthyridin-4(5H)-one (CAS 139482-44-3)
- 4-Methyl-3-((4-methylbenzyl)thio)-5-(3-(trifluoromethyl)phenyl)-4H-1,2,4-triazole (CAS 778589-13-2)
- 2-((4-Methylbenzyl)amino)-2-oxoethyl 5-bromonicotinate (CAS 733018-03-6)
- 2-((4-Methylbenzyl)thio)-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 626227-69-8)
- Methyl 4-(4-(4-methylbenzyl)piperazin-1-yl)-3-nitrobenzoate (CAS 478246-63-8)
- 4-[(4-Methylbenzyl)oxy]-N-[(E,2Z)-3-phenyl-2-propenylidene]benzenecarbohydrazide (CAS 320423-65-2)
- 3-[(4-Methylbenzyl)sulfanyl]-1-(2-methylphenyl)-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile (CAS 439107-25-2)
- 3-Ethyl-2-((3-methylbenzyl)thio)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (CAS 618879-73-5)
Recommended Standards
- 1-Benzyl-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-sulfonyl chloride (CAS 1334147-57-7)
- 2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-(pyridin-4-yl)-1,2-dihydro-3H-pyrazol-3-one (CAS 219138-24-6)
- tert-Butyl 4-(6-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine-1-carboxylate (CAS 625843-75-6)
- 3-(4-Fluorophenyl)-1H-pyrazole-4-carbaldehyde N-(7-chloro-4-quinolinyl)hydrazone (CAS 477711-39-0)
- (R)-(1-aminoethyl)boronic acid (CAS 149251-82-1)
- 3-(Methylsulfamoyl)phenylboronic Acid (CAS 871329-75-8)
- Delta-Nonanolactone (CAS 3301-94-8)
- Bromhexine impurity 62 (CAS CATO-C4X-106062)
- 1-(5-(2-Hydroxy-3-methoxyphenyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)butan-1-one (CAS 923221-34-5)
- Methyl 3-fluoro-8-hydroxyquinoline-6-carboxylate (CAS 2721373-10-8)
- 3-Fluoro-N,2-dimethylaniline (CAS 881848-76-6)
- Methyl 2-(3-(2-bromophenyl)-1H-1,2,4-triazol-1-yl)acetate (CAS 1416344-31-4)
- (5-chlorothiophen-2-yl)(4-fluorophenyl)methanone (CAS 57931-93-8)
- Casein kinase II peptide Substrate (CAS 154444-98-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com