8-Chloro-3-iodo-5-nitroquinoline CAS 1334147-95-3
| CAS No. | 1334147-95-3 |
| Molecular Formula | C9H4ClIN2O2 |
| Molecular Weight | 334.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 334.50 g/mol gives 8-Chloro-3-iodo-5-nitroquinoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 8-Chloro-3-iodo-5-nitroquinoline (CAS 1334147-95-3), a certified reference material (molecular formula C9H4ClIN2O2, MW 334.50 g/mol) for analytical method development and quality control.
The molecular framework of 8-Chloro-3-iodo-5-nitroquinoline (C9H4ClIN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H4ClIN2O2 |
| Molecular Weight | 334.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-Chloro-6-iodo-3-nitroquinoline (CAS 1345447-25-7)
- 4-Chloro-8-iodo-3-nitroquinoline (CAS 1596824-22-4)
- 1-(3-Chloro-4-iodophenyl)-2,2,2-trifluoroethan-1-one (CAS 2352970-26-2)
- 1-(5-Chloro-2-iodophenyl)-2,2,2-trifluoroethan-1-one (CAS 2352648-31-6)
- 4-Chloro-6-iodo-7-methoxy-2-methylquinazoline (CAS 2230840-19-2)
- 2-Chloro-4-(difluoromethyl)-3-iodo-5-nitropyridine (CAS 1805062-22-9)
- 4-Chloro-3-(difluoromethyl)-2-iodo-5-nitropyridine (CAS 1805261-99-7)
- 2-Chloro-3-(difluoromethyl)-6-iodo-4-nitropyridine (CAS 1805270-36-3)
Recommended Standards
- 3-(N-Acetylamino)-5-(N-decyl-N-methylamino)benzyl Alcohol (CAS 103955-90-4)
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- N-Cyclohexyl-3-(2-methyl-4-(thiophen-2-yl)thiazol-5-yl)propanamide (CAS 1017662-82-6)
- (2S)-6-(5-(1,2-Dithiolan-3-yl)pentanamido)-2-aminohexanoic acid (CAS 1676-89-7)
- (2,5-Dimethoxypyrimidin-4-yl)boronic acid (CAS 478692-50-1)
- 3-Cyclopropyl-5-isothiazolecarboxylic acid (CAS 1781933-78-5)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-phenethylacetamide (CAS 383148-71-8)
- 1,2-Diphenylethane-1,2-diamine (CAS 5700-60-7)
- 2-(2-Chloro-4-(difluoromethyl)-5-hydroxypyridin-3-yl)acetic acid (CAS 1805058-37-0)
- 1-(3-Methylpyridin-2-yl)cyclopropane-1-carboxylic acid (CAS 1402232-84-1)
- 4,5,5,5-Tetrafluoro-4-(trifluoromethoxy)-pent-2-enoic acid (CAS 261760-20-7)
- 2-Bromo-N-{3-[(2-phenoxyacetyl)amino]-phenyl}acetamide (CAS 1138443-07-8)
- 2-Methoxy-2-(1,3-thiazol-2-yl)ethan-1-amine (CAS 933751-34-9)
- Semaglutide impurity 43 (CAS CATO-C4X-222643)
Why CATO?
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