8-Fluoro-3-iodo-5-nitroquinoline CAS 1334148-68-3
| CAS No. | 1334148-68-3 |
| Molecular Formula | C9H4FIN2O2 |
| Molecular Weight | 318.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 8-Fluoro-3-iodo-5-nitroquinoline is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 8-Fluoro-3-iodo-5-nitroquinoline (CAS 1334148-68-3), a certified reference material (molecular formula C9H4FIN2O2, MW 318.04 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, 8-Fluoro-3-iodo-5-nitroquinoline is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 318.04 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H4FIN2O2 |
| Molecular Weight | 318.04 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
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- 4-Fluoro-3-iodo-2-(trifluoromethyl)benzaldehyde (CAS 1539315-05-3)
- 5-Fluoro-2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-7-carboxamide (CAS 2750996-89-3)
- 7-Fluoro-3-isopropyl-2-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-indazole (CAS 2620710-80-5)
- cis-2-(3-Fluoro-5-(trifluoromethyl)benzoyl)cyclohexanecarboxylic acid (CAS 1443312-34-2)
- 6-Fluoro-1-(2-fluoroethyl)-4-oxo-7-(1H-pyrrol-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 106221-35-6)
- Methyl 2-fluoro-4-[3-methoxy-5-(methoxycarbonyl)phenyl]benzoate (CAS 1820603-46-0)
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Recommended Standards
- 4,4'-DDE (CAS 72-55-9)
- 5-Iodo-4-methoxy-2-methyl-6-(trifluoromethyl)pyrimidine (CAS 792934-97-5)
- 2,4＇-DDE (CAS 3424-82-6)
- (3,5-Dichloro-4-nitrophenyl)pentafluoro-lambda6-sulfane (CAS 1431329-68-8)
- 2-(3-Ethoxyphenyl)-4-methylpyrrolidine (CAS 603068-22-0)
- 3-Chloro-5-(2-methoxyphenyl)-7-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 695191-62-9)
- 2-(((3-Chlorobenzyl)oxy)methyl)piperidine hydrochloride (CAS 1261233-18-4)
- N-(3-Phenyl-5-thioxo-1H-1,2,4-triazol-4(5H)-yl)acetamide (CAS 99072-82-9)
- N,N'-BIs[(1R)-1-phenylethyl]sulfamide (CAS 91410-68-3)
- 2,2',3,4,4',5,5'-Heptachloro[13C12]biphenyl (CAS 160901-82-6)
- 5-(4-Chloro-2-methoxyphenyl)-5-oxovaleric acid (CAS 951889-68-2)
- D-Myo-inositol 1,3,4-triphosphate hexapotassium salt (CAS 140385-74-6)
- (3-Amino-2,2-dimethyl-3-oxopropyl)carbamic Acid Phenylmethyl Ester 3-[(Benzyloxycarbonyl)amino]-2,2-di(methyl)propionamide 3N-Benzyloxycarbonyl 3-Amino-2,2-dimethylpropanamide 666844-61-7 N-(3-Amino-2,2-dimethyl-3-oxopropyl)carbamic Acid Benzyl Ester (CAS 666844-61-7)
- Semaglutide Impurity 14(Discontinued,See CPTD788307 ) (CAS CATO-C4X-222614)
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