2-(1-(tert-Butoxycarbonyl)-4,4-difluoropiperidin-3-yl)acetic acid CAS 1334417-29-6
| CAS No. | 1334417-29-6 |
| Molecular Formula | C12H19F2NO4 |
| Molecular Weight | 279.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 279.28 g/mol gives 2-(1-(tert-Butoxycarbonyl)-4,4-difluoropiperidin-3-yl)acetic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(1-(tert-Butoxycarbonyl)-4,4-difluoropiperidin-3-yl)acetic acid (CAS 1334417-29-6) is a high-purity analytical reference standard with the molecular formula C12H19F2NO4 and a molecular weight of 279.28 g/mol.
The molecular framework of 2-(1-(tert-Butoxycarbonyl)-4,4-difluoropiperidin-3-yl)acetic acid (C12H19F2NO4) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(1-(tert-Butoxycarbonyl)-4,4-difluoropiperidin-3-yl)acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H19F2NO4 |
| Molecular Weight | 279.28 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related tert Standards
- 1-(tert-Butoxycarbonyl)-3,3-difluoro-4-methylpiperidine-4-carboxylic acid (CAS 1334414-61-7)
- 1-(Tert-butoxycarbonyl)-5,5-difluoro-3-methylpiperidine-3-carboxylic acid (CAS 1359656-96-4)
- 1-(Tert-butoxycarbonyl)-5,5-difluoroazepane-4-carboxylic acid (CAS 1781115-34-1)
- 2-(1-(Tert-butoxycarbonyl)piperidin-3-yl)-2,2-difluoroacetic acid (CAS 1782406-03-4)
- 1-((Tert-butoxycarbonyl)amino)-3,3-difluorocyclohexane-1-carboxylic acid (CAS 2306261-00-5)
- 1-(Tert-butoxycarbonyl)-2-ethyl-4,4-difluoropyrrolidine-2-carboxylic acid (CAS 2173992-55-5)
- 1-(tert-Butoxycarbonyl)-4-(difluoromethyl)piperidine-2-carboxylic acid (CAS 2701544-45-6)
- 1-(Tert-butoxycarbonyl)-4,4-difluoro-3,3-dimethylpyrrolidine-2-carboxylic acid (CAS 905302-02-5)
Recommended Standards
- 1-[(tert-Butoxy)carbonyl]-4,4-difluoro-3-methylpiperidine-3-carboxylic acid (CAS 1334416-85-1)
- 2-(4-(Trifluoromethyl)phenyl)benzo[d]thiazole (CAS 134384-31-9)
- 1-(Tert-butyl) 2-methyl (S)-4,4-difluoropiperidine-1,2-dicarboxylate (CAS 1352342-07-4)
- 2-(3-(Trifluoromethyl)phenyl)benzo[d]thiazole (CAS 133389-19-2)
- 5-Cyclopropyl-1H-Indole (CAS 893739-92-9)
- Tert-butyl 4-(2,4-dichlorophenyl)piperazine-1-carboxylate (CAS 1121599-74-3)
- Dibromo Malonamide (CAS 73003-80-2)
- 4-([1,1'-Biphenyl]-4-yl)-2,6-dichloropyrimidine (CAS 1385826-81-2)
- 1h-Indazole-4-carbohydrazide (CAS 1086392-16-6)
- (R)-1-(5-chloro-2-fluorophenyl)-2-methoxyethan-1-amine (CAS 1270177-78-0)
- 3,9-diazaspiro[5.5]undecane-2,4-dione hydrochloride (CAS 1193388-13-4)
- 1-Amino-4-bromopyridinium iodide (CAS 1533440-88-8)
- Methyl 2-methyl-3-phenylacrylate (CAS 25692-59-5)
- [Tyr0] Fibrinopeptide A, human (CAS 103226-11-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com