4,4,5,5-Tetramethyl-2-[4-(1-methylethoxy)-3-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane CAS 1334607-79-2
| CAS No. | 1334607-79-2 |
| Molecular Formula | C16H22BF3O3 |
| Molecular Weight | 330.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 4,4,5,5-Tetramethyl-2-[4-(1-methylethoxy)-3-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane (CAS 1334607-79-2), a certified reference material (molecular formula C16H22BF3O3, MW 330.15 g/mol) for analytical method development and quality control.
Based on its molecular formula C16H22BF3O3, 4,4,5,5-Tetramethyl-2-[4-(1-methylethoxy)-3-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 330.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C16H22BF3O3 |
| Molecular Weight | 330.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related Tetramethyl Standards
- 4,4,5,5-Tetramethyl-2-(4-propoxy-2-(trifluoromethyl)phenyl)-1,3,2-dioxaborolane (CAS 1186482-12-1)
- 4,4,5,5-Tetramethyl-2-[4-(pentafluorosulfanyl)phenyl]-1,3,2-dioxaborolane (CAS 1286278-34-9)
- 4,4,5,5-Tetramethyl-2-(m-pentafluorosulfanylbenzene)-1,3,2-dioxaborolane (CAS 1286278-35-0)
- Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)benzoate (CAS 1150271-61-6)
- Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)benzoate (CAS 1671078-38-8)
- Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)benzoate (CAS 1810790-95-4)
- Methyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)benzoate (CAS 873846-89-0)
- 3-Methyl-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)imidazolidine-2,4-dione (CAS 1295301-38-0)
Recommended Standards
- 2-{1-[(4-bromo-3-fluorophenyl)carbonyl]pyrrolidin-2-yl}acetic acid (CAS 1283631-20-8)
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- 1-(4-Bromo-3-fluorobenzoyl)piperidine-2-carboxylic acid (CAS 1283338-12-4)
- (E)-5-(3-Bromo-4-hydroxy-5-methoxybenzylidene)thiazolidine-2,4-dione (CAS 58215-62-6)
- 4-Chloro-6,7-dimethylpteridine (CAS 32587-03-4)
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- (S)-tert-Butyl 1-aminopiperidine-3-carboxylate (CAS 1225349-89-2)
- 5-Amino-1-(2-methylphenyl)-1H-pyrazole-4-carbonitrile (CAS 142893-46-7)
- 4-Chloro-5-(cyclohexyloxy)pyridazin-3(2H)-one (CAS 1346697-57-1)
- 3-Amino-3-(3-cyclopentyl-1-methyl-1h-1,2,4-triazol-5-yl)propan-1-ol (CAS 1344280-72-3)
- Methyl 2-(2-formyl-6-methoxyphenoxy)acetate (CAS 40359-29-3)
- 2-(Difluoromethyl)cyclobutan-1-amine hydrochloride (CAS 2138430-22-3)
- D-β-Asp9-Tirzepatide (CAS CATO-CPTD788932)
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