4-Nitro-2-phenylpyridine CAS 1335110-45-6
| CAS No. | 1335110-45-6 |
| Molecular Formula | C11H8N2O2 |
| Molecular Weight | 200.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Nitro-2-phenylpyridine (C11H8N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-Nitro-2-phenylpyridine (CAS 1335110-45-6), molecular formula C11H8N2O2 and molecular weight 200.19 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Nitro-2-phenylpyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8N2O2 |
| Molecular Weight | 200.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
Related Nitro Standards
- 3-Nitro-2-phenylpyridine (CAS 134896-35-8)
- 3-Nitro-4-phenylpyridine (CAS 220952-00-1)
- 5-Nitro-2-phenylpyridine (CAS 89076-64-2)
- 6-NITRO-2H-1,4-BENZOXAZIN-3(4H)-ONE 6-nitro-2H-benzo[b][1,4]oxazin-3(4H)-one 81721-87-1 (CAS 81721-87-1)
- 3-(3-nitro-1h-1,2,4-triaZol-1-yl)propanohydrazide (CAS 832740-05-3)
- 2-((5-Methyl-4-nitro-1,2-dihydro-3h-pyrazol-3-ylidene)amino)acetic acid (CAS 1046468-89-6)
- methyl 3-(3-nitro-1h-1,2,4-triaZol-1-yl)propanoate (CAS 105958-58-5)
- 6-nitro-1H,2H,3H,4H-pyrrolo[2,1-f][1,2,4]triazine-2,4-dione (CAS 1245644-73-8)
Recommended Standards
- Dimethyl (E)-2-(3-methoxyallylidene)malonate (CAS 133445-85-9)
- Ethyl 5-(ethoxymethyl)-1,2,4-oxadiazole-3-carboxylate (CAS 1341068-81-2)
- 5-(1-Benzofuran-2-yl)-3-methyl-1,2,4-oxadiazole (CAS 1283108-87-1)
- 5-(2-Propoxyethyl)-1,2,4-oxadiazole-3-carboxylic acid (CAS 1343153-98-9)
- Methyl 5-amino-2-[4-benzyl-2-(propan-2-yl)piperazin-1-yl]benzoate (CAS 1242262-11-8)
- 3-Methyl-1-phenyl-5-(piperidin-1-yl)-1h-pyrazole-4-carbaldehyde (CAS 5499-70-7)
- Tert-butyl (2-hydroxy-3-(hydroxymethyl)phenethyl)(propyl)carbamate (CAS 1638760-55-0)
- 1-(4-{[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}phenyl)-1H-imidazole (CAS 320416-54-4)
- Tocopherol impurity 34 (CAS CATO-C4X-119534)
- 3-(3,4-Dihydro-2H-pyrrol-5-yl)-N-ethyl-N-methylpyridin-2-amine (CAS 1352484-11-7)
- 2-[(4-Butoxyphenyl)methylene]hydrazinecarbothioamide (CAS 100318-30-7)
- 1-[2-Amino-4-(thiophen-2-yl)-1,3-thiazol-5-yl]-2,2,2-trifluoroethan-1-one (CAS 306289-61-2)
- Methyl 1-amino-5-carbamoyl-1H-pyrrole-3-carboxylate (CAS 1204245-38-4)
- Gastrin Tetrapeptide (CAS 1947-37-1)
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