6-Chloro-2-(methylamino)-1,8-naphthyridine-3-carbonitrile CAS 1335112-96-3
| CAS No. | 1335112-96-3 |
| Molecular Formula | C10H7ClN4 |
| Molecular Weight | 218.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Chloro-2-(methylamino)-1,8-naphthyridine-3-carbonitrile (CAS 1335112-96-3), molecular formula C10H7ClN4 and molecular weight 218.64 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Chloro-2-(methylamino)-1,8-naphthyridine-3-carbonitrile (C10H7ClN4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Chloro-2-(methylamino)-1,8-naphthyridine-3-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7ClN4 |
| Molecular Weight | 218.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
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- 8-chloro-6-methyl-4-oxo-1,4-dihydroquinoline-3-carbonitrile (CAS 1016827-93-2)
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Recommended Standards
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- methyl 4-[3-(chloromethyl)-1,2,4-oxadiazol-5-yl]butanoate (CAS 1311314-51-8)
- 4-Chloro-6-methoxyquinoline-3-carbonitrile (CAS 13669-62-0)
- 2-(5-Bromo-1h-indol-3-yl)ethan-1-amine (CAS 3610-42-2)
- 1H,2H,2AH,3H,4H,8bH-cyclobuta[a]naphthalen-2-one (CAS 88336-60-1)
- Tert-butyl (4-(2-hydroxypyridin-3-yl)phenyl)carbamate (CAS 1261896-32-5)
- 4-(Trifluoromethylthio)benzyl Bromide (CAS 21101-63-3)
- 3-Morpholino-N-((1-propyl-1H-pyrazol-4-yl)methyl)propan-1-amine dihydrochloride (CAS 1856064-58-8)
- ethyl 5-hydroxypyrazine-2-carboxylate (CAS 54013-03-5)
- 4-(Ethylamino)-2-methyl-2-butanol (CAS 914261-17-9)
- Ethyl 6-(cyclopropylamino)nicotinate (CAS 1033619-73-6)
- 1-[(4-Ethylsulfonyl-2-fluoro)phenyl]piperazine (CAS 845617-58-5)
- [Tyr15] Fibrinopeptide B, human (CAS 125455-56-3)
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