(R)-4-chloro-6,7-dihydro-5H-cyclopenta[b]pyridin-7-amine CAS 1335816-18-6
| CAS No. | 1335816-18-6 |
| Molecular Formula | C8H9ClN2 |
| Molecular Weight | 168.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (R)-4-chloro-6,7-dihydro-5H-cyclopenta[b]pyridin-7-amine (C8H9ClN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
(R)-4-chloro-6,7-dihydro-5H-cyclopenta[b]pyridin-7-amine (CAS 1335816-18-6) is a high-purity analytical reference standard with the molecular formula C8H9ClN2 and a molecular weight of 168.62 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (R)-4-chloro-6,7-dihydro-5H-cyclopenta[b]pyridin-7-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H9ClN2 |
| Molecular Weight | 168.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 2-Chloro-5-ethylbenzaldehyde (CAS 1289207-94-8)
- (S)-2-chloro-6,7-dihydro-5H-cyclopenta[b]pyridin-7-amine (CAS 1336012-60-2)
- (S)-7-Chloro-2,3-dihydro-1H-inden-1-ol (CAS 1270301-79-5)
- (R)-2-chloro-6,7-dihydro-5H-cyclopenta[b]pyridin-7-amine (CAS 1336222-56-0)
- 6,7-Dihydro-5H-pyrrolo[1,2-c]imidazol-7-ol (CAS 2098584-35-9)
- 3-Benzyl-5-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-2,3-dihydro-1,3,4-oxadiazol-2-one (CAS 866152-88-7)
- 4-(1-Naphthyl)phenylboronic Acid (CAS 870774-25-7)
- 4-Bromo-6-(4-fluorophenyl)pyrimidine (CAS 85979-65-3)
- Oritavancin Phosphate (CAS 171099-57-3(free base))
- 439109-81-6 6-Hydroxy-1-methyl-2-oxo-1,2-dihydro-4-pyrimidinecarboxylic acid MFCD00244509 (CAS 439109-81-6)
- 3-Amino-1,1,1-trifluorobutan-2-ol (CAS 129681-16-9)
- tert-butyl 4-[5-(hydroxymethyl)-1,2-oxazol-3-yl]piperidine-1-carboxylate (CAS 2031258-93-0)
- 3-(3,5-Difluorophenyl)benzonitrile (CAS 1266996-50-2)
- Semaglutide impurity 55 (CAS CATO-C4X-222655)
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