5-Bromo-7-fluoro-3,4-dihydronaphthalen-2(1H)-one CAS 1336954-16-5
| CAS No. | 1336954-16-5 |
| Molecular Formula | C10H8BrFO |
| Molecular Weight | 243.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 5-Bromo-7-fluoro-3,4-dihydronaphthalen-2(1H)-one (C10H8BrFO) contains a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 243.07 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
5-Bromo-7-fluoro-3,4-dihydronaphthalen-2(1H)-one (CAS 1336954-16-5), molecular formula C10H8BrFO and molecular weight 243.07 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8BrFO |
| Molecular Weight | 243.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- (5-Bromo-2-fluorophenyl)(cyclopropyl)methanone (CAS 1222368-75-3)
- 5-Bromo-6-fluoro-3,4-dihydronaphthalen-1(2H)-one (CAS 1260007-55-3)
- 5-Bromo-8-fluoro-3,4-dihydronaphthalen-1(2H)-one (CAS 1260010-73-8)
- 6-Bromo-5-fluoro-3,4-dihydronaphthalen-1(2H)-one (CAS 1260013-62-4)
- 6-Bromo-7-fluoro-3,4-dihydronaphthalen-1(2H)-one (CAS 1260014-69-4)
- 7-Bromo-6-fluoro-3,4-dihydronaphthalen-1(2H)-one (CAS 1260014-75-2)
- 7-Bromo-6-fluoro-3,4-dihydronaphthalen-2(1h)-one (CAS 1337854-09-7)
- 6-Bromo-8-fluoro-3,4-dihydronaphthalen-2(1H)-one (CAS 1337857-08-5)
Recommended Standards
- (6-(Benzyloxy)-5-methylpyridin-3-yl)boronic acid (CAS 1356087-42-7)
- (3-Bromo-2-fluorophenyl)(cyclopropyl)methanone (CAS 1428881-43-9)
- (6-(Benzyloxy)-4-methylpyridin-3-yl)boronic acid (CAS 1451391-35-7)
- 6-Bromo-4-fluoro-2-methyl-2,3-dihydro-1h-inden-1-one (CAS 1509338-41-3)
- (2Z)-2-[(Thiophen-2-yl)methylidene]-1-azabicyclo[2.2.2]octan-3-ol (CAS 929256-69-9)
- [2-(4-Butoxyphenoxy)ethyl]amine hydrochloride (CAS 1134922-34-1)
- Methyl 2-amino-5-(4-methoxyphenyl)-4-methylthiophene-3-carboxylate (CAS 358739-97-6)
- (5-Bromopyridin-3-yl)(imino)(methyl)-l6-sulfanone (CAS 2361936-19-6)
- 5-acetylpyridine-2-carbonitrile (CAS 249583-84-4)
- 3-Amino-2-((1-methyl-1h-pyrazol-4-yl)methyl)propan-1-ol (CAS 1152820-32-0)
- Azilsartan Impurity 69 (CAS 91526-18-0)
- (S)-1-Amino-5-((trityloxy)methyl)pyrrolidin-2-one (CAS 1190392-77-8)
- 5,7-Dimethylpyrazolo[1,5-a]pyrimidine-2-carboxylic acid hydrochloride (CAS 2189434-98-6)
- Semaglutide Impurity 82 (CAS CATO-C4X-222682)
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