3-[(3,4-difluorophenyl)methyl]pyrrolidine CAS 1337018-79-7
| CAS No. | 1337018-79-7 |
| Molecular Formula | C11H13F2N |
| Molecular Weight | 197.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-[(3,4-difluorophenyl)methyl]pyrrolidine (CAS 1337018-79-7) is a high-purity analytical reference standard with the molecular formula C11H13F2N and a molecular weight of 197.22 g/mol.
3-[(3,4-difluorophenyl)methyl]pyrrolidine (C11H13F2N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 3-[(3,4-difluorophenyl)methyl]pyrrolidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H13F2N |
| Molecular Weight | 197.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related difluorophenyl Standards
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- 2-(2,6-Difluorophenyl)piperidine (CAS 1016716-11-2)
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- 4-(2,6-Difluorophenyl)piperidine (CAS 1019373-70-6)
- n-(1-(2,4-Difluorophenyl)ethyl)prop-2-en-1-amine (CAS 1019537-98-4)
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- 3-(2,4-Difluorophenyl)piperidine (CAS 1044768-67-3)
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Recommended Standards
- 1-(2-(2,6-Difluorophenyl)cyclopropyl)-N-methylmethanamine (CAS 1312132-85-6)
- 3-(2,3-Difluorobenzyl)pyrrolidine (CAS 1337289-05-0)
- 4,4-Difluoro-2-phenylpiperidine (CAS 1257301-37-3)
- 3-(2,6-Difluorobenzyl)pyrrolidine (CAS 1337673-70-7)
- Propyl[(pyridin-4-yl)methyl]amine hydrochloride (CAS 405879-15-4)
- N-Methylacridin-9-amine (CAS 22739-29-3)
- 3-(3-Chlorophenoxy)pyrrolidine (CAS 337912-67-1)
- 4-{[(2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)amino]methyl}benzonitrile (CAS 1157387-72-8)
- 5-Bromo-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridin-6(7H)-one (CAS 1437385-30-2)
- 1-[4-(3-methoxyphenyl)-1h-imidazol-2-yl]ethan-1-amine dihydrochloride (CAS 1173036-46-8)
- 1,1',1''-(1,3,5-Triazinane-1,3,5-triyl)tris(propan-1-one) (CAS 30805-19-7)
- 5-Cyanospiro[2.3]hexane-5-carboxylic acid (CAS 1491982-69-4)
- 4-Amino-3-((tert-butoxycarbonyl)amino)benzoic acid (CAS 1282523-83-4)
- Peptide 432 (CAS CATO-CPTD788432)
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