6,6'-Thiobis(4-(tert-butyl)-2-(hydroxymethyl)phenol) CAS 133786-63-7
| CAS No. | 133786-63-7 |
| Molecular Formula | C22H30O4S |
| Molecular Weight | 390.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6,6'-Thiobis(4-(tert-butyl)-2-(hydroxymethyl)phenol) (CAS 133786-63-7) is a high-purity analytical reference standard with the molecular formula C22H30O4S and a molecular weight of 390.54 g/mol.
The molecular framework of 6,6'-Thiobis(4-(tert-butyl)-2-(hydroxymethyl)phenol) (C22H30O4S) is characterized by a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H30O4S |
| Molecular Weight | 390.54 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Sulfur Atoms | 1 |
Related Thiobis Standards
- 4,4'-Thiobis(benzene-1-sulfonyl chloride) (CAS 3119-65-1)
- 6,6'-Thiobis(4-chloro-2-nitrophenol) (CAS 852-20-0)
- 4,4'-Thiobis(2-(tert-butyl)-6-methylphenol) (CAS 96-66-2)
- 4,4＇-Thiobis(6-tert-butyl-m-cresol) (CAS 96-69-5)
- 2,2'-Thiobis(1-(4-bromophenyl)ethan-1-one) (CAS 58881-56-4)
- 2,2'-Thiobis(4-tert-octylphenol) (CAS 3294-03-9)
- 5,5'-Thiobis(isobenzofuran-1,3-dione) (CAS 25884-43-9)
- 2,2'-Thiobis(isoindoline-1,3-dione) (CAS 7764-29-6)
Recommended Standards
- [2,6-Bis(1-methylethoxy)phenyl]dicyclohexylphosphine (CAS 1268824-69-6)
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- (S)-2-(3-(1-((tert-Butylsulfonyl)methyl)cyclohexyl)ureido)-3,3-dimethylbutanoic acid, 97% (CAS 1208245-85-5)
- 1-(1-Methyl-3-phenyl-5-(p-tolylthio)-1H-pyrazol-4-yl)hept-2-yn-1-ol (CAS 318949-13-2)
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- 3-butyl-5-(1-chloroethyl)-1,2,4-oxadiazole (CAS 119738-10-2)
- 2,3-Diaminopyrrolo[2,3-b]pyrrol-1(6H)-ol (CAS 877396-80-0)
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