2-(2,6-Dichlorophenyl)-2,3-dihydro-3-hydroxypyrrolo[3,4-c]pyridin-1-one CAS 1337881-94-3
| CAS No. | 1337881-94-3 |
| Molecular Formula | C13H8Cl2N2O2 |
| Molecular Weight | 295.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2,6-Dichlorophenyl)-2,3-dihydro-3-hydroxypyrrolo[3,4-c]pyridin-1-one.
2-(2,6-Dichlorophenyl)-2,3-dihydro-3-hydroxypyrrolo[3,4-c]pyridin-1-one (CAS 1337881-94-3) is a high-purity analytical reference standard with the molecular formula C13H8Cl2N2O2 and a molecular weight of 295.12 g/mol.
The molecular framework of 2-(2,6-Dichlorophenyl)-2,3-dihydro-3-hydroxypyrrolo[3,4-c]pyridin-1-one (C13H8Cl2N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(2,6-Dichlorophenyl)-2,3-dihydro-3-hydroxypyrrolo[3,4-c]pyridin-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H8Cl2N2O2 |
| Molecular Weight | 295.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichlorophenyl Standards
- 2-(2,3-Dichlorophenyl)-2-oxoacetic acid (CAS 93942-57-5)
- 3-(3,4-Dichlorophenyl)-3-hydroxyisobenzofuran-1(3H)-one (CAS 393085-34-2)
- N~5~-(2,4-dichlorophenyl)-5H-pyrazolo[3,4-d]pyrimidine-4,5-diamine (CAS 338403-46-6)
- (2E)-1-(2,5-Dichlorophenyl)-3-(2-fluorophenyl)prop-2-en-1-one (CAS 1001578-73-9)
- (2E)-1-(2,5-Dichlorophenyl)-3-(4-fluorophenyl)prop-2-en-1-one (CAS 1003452-55-8)
- (2E)-1-(2,4-Dichlorophenyl)-3-(4-fluorophenyl)prop-2-en-1-one (CAS 1177802-59-3)
- (2E)-1-(3,4-Dichlorophenyl)-3-(4-fluorophenyl)prop-2-en-1-one (CAS 1208986-01-9)
- 1-(3,5-Dichlorophenyl)-3-(4-fluorophenyl)prop-2-en-1-one (CAS 1217245-43-6)
Recommended Standards
- 6-Iodo-3,4-dihydro-2H-pyrano[3,2-b]pyridine-8-carbaldehyde (CAS 1261365-84-7)
- 6-Chloro-2-(3-chloro-4-methoxyphenyl)oxazolo[5,4-b]pyridine (CAS 1354749-96-4)
- 1-(2,4-Dichlorobenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ol (CAS 125240-57-5)
- 3-iodo-1h-indole-7-carboxylic acid (CAS 1360953-77-0)
- ethyl 2-chloro-6-iodo-1,8-naphthyridine-3-carboxylate (CAS 1330583-63-5)
- 6,8-Dichloro-2-(2-methoxyphenyl)imidazo[1,2-a]pyridine (CAS 353258-15-8)
- 2-[N-[2-(Fmoc-amino)ethyl]-2-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamido]acetic Acid (CAS 169396-92-3)
- 4,4,4-(Pyridine-2,4,6-triyl)tribenzaldehyde (CAS 2230887-26-8)
- 2-Chloro-4-ethylthiazole (CAS 98025-12-8)
- [4'-[4-[[[[(R)-1-(2-Chlorophenyl)ethyl]oxy]carbonyl]amino]-3-methylisoxazol-5-yl]biphenyl-4-yl]acetic acid ethyl ester (CAS 1228690-21-8)
- Fluorouracil EP Impurity F (CAS 56177-80-1)
- Mordant Brown 1Discontinued (CAS 3564-15-6)
- 2-(5-(2-Aminoethyl)-1,2,4-oxadiazol-3-yl)-N,N-dimethylacetamide (CAS 1437434-57-5)
- Semaglutide Impurity 155 (x TFA Salt) (CAS CATO-C4X-2226155)
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