5-Chloro-3-[2-(trifluoromethyl)phenyl]-1,2,4-thiadiazole CAS 1338218-73-7
| CAS No. | 1338218-73-7 |
| Molecular Formula | C9H4ClF3N2S |
| Molecular Weight | 264.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Chloro-3-[2-(trifluoromethyl)phenyl]-1,2,4-thiadiazole.
CATO supplies 5-Chloro-3-[2-(trifluoromethyl)phenyl]-1,2,4-thiadiazole (CAS 1338218-73-7), a certified reference material (molecular formula C9H4ClF3N2S, MW 264.65 g/mol) for analytical method development and quality control.
5-Chloro-3-[2-(trifluoromethyl)phenyl]-1,2,4-thiadiazole (C9H4ClF3N2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Chloro-3-[2-(trifluoromethyl)phenyl]-1,2,4-thiadiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H4ClF3N2S |
| Molecular Weight | 264.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 5-Chloro-3-[4-(trifluoromethyl)phenyl]-1,2,4-thiadiazole (CAS 138426-23-0)
- 5-Chloro-3-[3-(trifluoromethyl)phenyl]-1,2,4-thiadiazole (CAS 138426-29-6)
- 3-Chloro-2-(trifluoromethyl)-4H-chromene-4-thione (CAS 869986-01-6)
- 3-Chloro-6-(thiophen-2-yl)-4-(trifluoromethyl)pyridazine (CAS 929971-91-5)
- 1-(3-Chloro-4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one (CAS 1082584-11-9)
- 2-(4-Chloro-5-cyclopropyl-3-(difluoromethyl)-1h-pyrazol-1-yl)acetohydrazide (CAS 1004643-39-3)
- 1-[(4-chloro-3-nitrophenyl)methyl]-1,2-dihydropyridin-2-one (CAS 1097788-36-7)
- 1-(3-chloro-4-cyanophenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 1097813-79-0)
Recommended Standards
- 5-(chlorosulfonyl)benzene-1,3-dicarboxylic acid (CAS 134178-04-4)
- 4-Carbamoyl-2-nitrobenzene-1-sulfonyl chloride (CAS 1248014-50-7)
- 6-(Trifluoromethyl)benzo[b]thiophene-2-carbonyl chloride (CAS 142329-19-9)
- N1-[6-chloro-5-(trifluoromethyl)-3-pyridyl]cyclopropane-1-carboxamide (CAS 680214-01-1)
- Ethyl 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate (CAS 52505-56-3)
- 3-[1-(2-carbamoylethyl)-3-(4-chlorophenyl)-1h-pyrazol-4-yl]-2-cyanoprop-2-enoic acid (CAS 1006493-20-4)
- 5-Amino-2-((5-methyl-1,3,4-thiadiazol-2-yl)amino)pyrimidin-4(1H)-one (CAS 77961-53-6)
- N-(4-((3,5-Dichlorophenyl)thio)phenyl)cyclopropanecarboxamide (CAS 1956317-89-7)
- N'-(2-Chlorobenzyl)-5-methylisoxazole-3-carbohydrazide (CAS 91396-23-5)
- Ethyl 5-methyl-4-phenoxypyrrolo[2,1-f][1,2,4]triazine-6-carboxylate (CAS 1363380-63-5)
- 2'-(((tert-Butoxycarbonyl)amino)methyl)-[1,1'-biphenyl]-4-carboxylic acid (CAS 1215034-62-0)
- 3-Methyl-3-phenylpentanedioic acid (CAS 4160-92-3)
- Ethyl 2-(4-formyl-2-nitrophenoxy)acetate (CAS 420786-61-4)
- Endo-Pro36-Tirzepatide (CAS CATO-CPTD788688)
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