1-(8-bromo-5-chloroisoquinolin-3-yl)-3-ethylurea CAS 1338254-49-1
| CAS No. | 1338254-49-1 |
| Molecular Formula | C12H11BrClN3O |
| Molecular Weight | 328.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(8-bromo-5-chloroisoquinolin-3-yl)-3-ethylurea (C12H11BrClN3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
1-(8-bromo-5-chloroisoquinolin-3-yl)-3-ethylurea (CAS 1338254-49-1) is a high-purity analytical reference standard with the molecular formula C12H11BrClN3O and a molecular weight of 328.59 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11BrClN3O |
| Molecular Weight | 328.59 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 3 |
Related bromo Standards
- Ethyl 6-bromo-4-chloro-8-methylquinoline-3-carboxylate (CAS 1016780-82-7)
- Ethyl 8-bromo-4-chloro-6-methylquinoline-3-carboxylate (CAS 1016828-40-2)
- 5-Bromo-2-chloro-N-(4-methoxybenzyl)pyrimidin-4-amine (CAS 1172925-32-4)
- 5-Bromo-2-chloro-N-((1-methyl-1h-pyrazol-5-yl)methyl)benzamide (CAS 1177223-00-5)
- 4-Bromo-6-chlorobenzo[d]thiazole-2-sulfonic acid (CAS 1226808-74-7)
- Ethyl 7-bromo-4-chloro-8-methylquinoline-3-carboxylate (CAS 1242260-50-9)
- Ethyl 4-bromo-5-chloro-8-methylquinoline-3-carboxylate (CAS 1242260-75-8)
- Ethyl 4-bromo-7-chloro-8-methylquinoline-3-carboxylate (CAS 1242260-84-9)
Recommended Standards
- 1-(5-bromo-8-chloroisoquinolin-3-yl)-3-ethylurea (CAS 1338254-29-7)
- 4-(7-Bromo-2-chloroquinazolin-4-yl)morpholine (CAS 1374208-34-0)
- 4-(8-Bromo-2-chloroquinazolin-4-yl)morpholine (CAS 1374208-47-5)
- Ethyl 8-bromo-4-chloro-7-methylquinoline-3-carboxylate (CAS 1529627-57-3)
- Flutriafol (CAS 76674-21-0)
- 5-Chloro-3-(3,5-difluorophenyl)-1,2,4-thiadiazole (CAS 1491356-45-6)
- 2,4-Dichloro-2-morpholinomethyl benzophenone (CAS 898751-01-4)
- Alpha,alpha-dithiocyanato-p-xylene (CAS 1014-99-9)
- 6-(5-Methylfuran-2-yl)-5-nitropyrimidine-2,4-diamine (CAS 442910-17-0)
- Methyl (2S,4S)-4-(3-chloro-4-fluorophenoxy)-2-pyrrolidinecarboxylate (CAS 1217813-37-0)
- 2-(3-Nitrophenyl)-N-propylacetamide (CAS 58730-53-3)
- N-(2,4-difluorophenyl)-1-(5-((4-fluorophenyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methanimine (CAS 477711-92-5)
- (E)-5,5'-(Ethene-1,2-diyl)diisophthalic acid (CAS 1025726-44-6)
- Galanin-Like Peptide (porcine) trifluoroacetate salt (CAS 245114-96-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com