Safinamide Impurity 32 CAS 133865-88-0
| CAS No. | 133865-88-0 |
| Molecular Formula | C17H19FN2O2 |
| Molecular Weight | 302.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Safinamide Impurity 32 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Safinamide Impurity 32 (CAS 133865-88-0, C17H19FN2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Safinamide Impurity 32 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 302.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Safinamide Impurity 32 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H19FN2O2 |
| Molecular Weight | 302.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Safinamide Standards
- Safinamide Impurity N1 (CAS 861398-52-9)
- Safinamide (CAS 133865-89-1)
- Safinamide Impurity 31 (CAS 202825-43-2)
- Safinamide impurity 54 (CAS CATO-C4X-159054)
- Safinamide Impurity 55 (CAS CATO-C4X-159055)
- Safinamide impurity 6 (CAS 174756-44-6)
- Safinamide Impurity 2 (CAS 1160513-60-9)
- Safinamide Impurity 22 (CAS 1000370-31-9)
Recommended Standards
- Propofol Impurity 51 (CAS CATO-C4X-147351)
- Azathioprine Impurity 14 (CAS 49808-20-0)
- Salicylic Acid Impurity 22 (CAS CATO-C4X-190222)
- Flurbiprofen Impurity 149 (CAS CATO-C4X-1444149)
- Mometasone Impurity 50 (CAS 23776-75-2)
- Norfloxacin Impurity 54 (CAS CATO-C4X-146854)
- Urapidil Impurity 84 (CAS CATO-C4X-192484)
- 7-Chloro-4-methoxy-1H-indole-2-carboxylic acid (CAS 383132-75-0)
- 2-(1,3-Dioxolan-2-yl)-1-(2-methoxyphenyl)ethan-1-one (CAS 1263365-46-3)
- 3-Methylimidazo[1,5-a]pyridine-6-carboxylic Acid (CAS 1260777-34-1)
- 4-(sec-Butylamino)quinazoline-2(1H)-thione (CAS 443348-18-3)
- 2-({2-[2-(2-Isopropyl-5-methylphenoxy)acetyl]hydrazino}carbonyl)cyclohexanecarboxylic acid (CAS 446844-47-9)
- 4-(3-Methoxypyrrolidin-1-yl)benzoic acid (CAS 1699005-09-8)
- Acetyl Tetrapeptide- 15 (CAS 928007-64-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com